ENSG00000114770


Homo sapiens

Features
Gene ID: ENSG00000114770
  
Biological name :ABCC5
  
Synonyms : ABCC5 / ATP binding cassette subfamily C member 5 / O15440
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q27.1
Gene start: 183919934
Gene end: 184018015
  
Corresponding Affymetrix probe sets: 1558460_at (Human Genome U133 Plus 2.0 Array)   209380_s_at (Human Genome U133 Plus 2.0 Array)   226363_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000404302
Ensembl peptide - ENSP00000403510
Ensembl peptide - ENSP00000404809
Ensembl peptide - ENSP00000416840
Ensembl peptide - ENSP00000409913
Ensembl peptide - ENSP00000265586
Ensembl peptide - ENSP00000333926
Ensembl peptide - ENSP00000371934
Ensembl peptide - ENSP00000376358
Ensembl peptide - ENSP00000390911
Ensembl peptide - ENSP00000399726
NCBI entrez gene - 10057     See in Manteia.
OMIM - 605251
RefSeq - XM_017005494
RefSeq - NM_001023587
RefSeq - NM_001320032
RefSeq - NM_005688
RefSeq - XM_005247058
RefSeq - XM_005247059
RefSeq - XM_011512314
RefSeq - XM_011512315
RefSeq - XM_017005492
RefSeq - XM_017005493
RefSeq Peptide - NP_001306961
RefSeq Peptide - NP_005679
RefSeq Peptide - NP_001018881
swissprot - F8WCY8
swissprot - F8WDH3
swissprot - H7C271
swissprot - A5PKY6
swissprot - O15440
swissprot - E9PET4
swissprot - C9JZL5
Ensembl - ENSG00000114770
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abcc5ENSDARG00000061233Danio rerio
 ABCC5ENSGALG00000008369Gallus gallus
 Abcc5ENSMUSG00000022822Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCC12 / Q96J65 / ATP binding cassette subfamily C member 12ENSG0000014079842
ABCC11 / Q96J66 / ATP binding cassette subfamily C member 11ENSG0000012127038
ABCC1 / P33527 / ATP binding cassette subfamily C member 1ENSG0000010322233
ABCC2 / Q92887 / ATP binding cassette subfamily C member 2ENSG0000002383933
ABCC3 / O15438 / ATP binding cassette subfamily C member 3ENSG0000010884632
ABCC4 / O15439 / ATP binding cassette subfamily C member 4ENSG0000012525732
ABCC8 / Q09428 / ATP binding cassette subfamily C member 8ENSG0000000607129
ABCC9 / O60706 / ATP binding cassette subfamily C member 9ENSG0000006943129
CFTR / P13569 / cystic fibrosis transmembrane conductance regulatorENSG0000000162624


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030238  Multidrug resistance-associated protein 5
 IPR036640  ABC transporter type 1, transmembrane domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015711 organic anion transport IEA
 biological_processGO:0030213 hyaluronan biosynthetic process TAS
 biological_processGO:0055085 transmembrane transport TAS
 biological_processGO:0099133 ATP hydrolysis coupled anion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding TAS
 molecular_functionGO:0008514 organic anion transmembrane transporter activity TAS
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA
 molecular_functionGO:0043225 ATPase-coupled anion transmembrane transporter activity TAS


Pathways (from Reactome)
Pathway description
Hyaluronan biosynthesis and export
ABC-family proteins mediated transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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