ENSGALG00000006219


Gallus gallus

Features
Gene ID: ENSGALG00000006219
  
Biological name :PRKAG2
  
Synonyms : 5-AMP-activated protein kinase subunit gamma-2 isoform 1 / PRKAG2
  
Possible biological names infered from orthology : protein kinase, AMP-activated, gamma 2 non-catalytic subunit / protein kinase AMP-activated non-catalytic subunit gamma 2 / Q91WG5 / Q9UGJ0
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 6325515
Gene end: 6507427
  
Corresponding Affymetrix probe sets: Gga.4517.1.S1_at (Chicken Array)   GgaAffx.12380.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000037978
Ensembl peptide - ENSGALP00000063610
Ensembl peptide - ENSGALP00000010021
Ensembl peptide - ENSGALP00000064395
Ensembl peptide - ENSGALP00000037988
Ensembl peptide - ENSGALP00000058135
NCBI entrez gene - 420435     See in Manteia.
RefSeq - XM_015281209
RefSeq - NM_001030965
RefSeq - NM_001278142
RefSeq - NM_001278143
RefSeq - XM_015281206
RefSeq - XM_015281207
RefSeq - XM_015281208
RefSeq Peptide - NP_001026136
RefSeq Peptide - NP_001265071
RefSeq Peptide - NP_001265072
swissprot - F1NXI9
swissprot - F1NXJ8
swissprot - F1NXL4
swissprot - Q3HLQ7
swissprot - Q5ZK07
swissprot - A0A1L1RXN3
Ensembl - ENSGALG00000006219
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prkag2aENSDARG00000012625Danio rerio
 prkag2bENSDARG00000001933Danio rerio
 PRKAG2ENSG00000106617Homo sapiens
 Prkag2ENSMUSG00000028944Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O54950* / P54619* / PRKAG1* / protein kinase AMP-activated non-catalytic subunit gamma 1* / protein kinase, AMP-activated, gamma 1 non-catalytic subunit*ENSGALG0000003628241
PRKAG3 / 5-AMP-activated protein kinase subunit gamma-3 / Q9UGI9* / Q8BGM7* / protein kinase AMP-activated non-catalytic subunit gamma 3* / protein kinase, AMP-activated, gamma 3 non-catat...ENSGALG0000001136038


Protein motifs (from Interpro)
Interpro ID Name
 IPR000644  CBS domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005977 glycogen metabolic process IEA
 biological_processGO:0006110 regulation of glycolytic process IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0019217 regulation of fatty acid metabolic process IEA
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0045860 positive regulation of protein kinase activity IEA
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IEA
 cellular_componentGO:0031588 nucleotide-activated protein kinase complex IEA
 molecular_functionGO:0004862 cAMP-dependent protein kinase inhibitor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008603 cAMP-dependent protein kinase regulator activity IEA
 molecular_functionGO:0008607 phosphorylase kinase regulator activity IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030295 protein kinase activator activity IEA
 molecular_functionGO:0043531 ADP binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
AMPK inhibits chREBP transcriptional activation activity
Import of palmitoyl-CoA into the mitochondrial matrix
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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