ENSGALG00000006237


Gallus gallus

Features
Gene ID: ENSGALG00000006237
  
Biological name :PKN2
  
Synonyms : PKN2 / protein kinase N2
  
Possible biological names infered from orthology : Q16513 / Q8BWW9 / Serine/threonine-protein kinase N2
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 15219523
Gene end: 15269342
  
Corresponding Affymetrix probe sets: Gga.19651.1.S1_at (Chicken Array)   Gga.19651.1.S1_s_at (Chicken Array)   Gga.2682.1.A1_at (Chicken Array)   Gga.2682.1.A1_s_at (Chicken Array)   Gga.8657.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010073
Ensembl peptide - ENSGALP00000055396
Ensembl peptide - ENSGALP00000050718
Ensembl peptide - ENSGALP00000050257
Ensembl peptide - ENSGALP00000045284
NCBI entrez gene - 424519     See in Manteia.
RefSeq - XM_015290644
swissprot - E1BYS6
swissprot - A0A1D5PR74
swissprot - A0A1D5PD75
swissprot - A0A1D5PBX5
swissprot - A0A1D5NY29
Ensembl - ENSGALG00000006237
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pkn2ENSDARG00000101983Danio rerio
 zgc:153916ENSDARG00000101293Danio rerio
 PKN2ENSG00000065243Homo sapiens
 Pkn2ENSMUSG00000004591Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PKN3 / protein kinase N3 / Q6P5Z2* / Q8K045* / Serine/threonine-protein kinase N3 *ENSGALG0000000468946


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011072  HR1 rho-binding domain
 IPR017441  Protein kinase, ATP binding site
 IPR017892  Protein kinase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010631 epithelial cell migration IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0032467 positive regulation of cytokinesis IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043297 apical junction assembly IEA
 biological_processGO:0045070 positive regulation of viral genome replication IEA
 biological_processGO:0045931 positive regulation of mitotic cell cycle IEA
 biological_processGO:2000145 regulation of cell motility IEA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030496 midbody IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043296 apical junction complex IEA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017049 GTP-Rho binding IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0070063 RNA polymerase binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases activate PKNs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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