ENSGALG00000006598


Gallus gallus

Features
Gene ID: ENSGALG00000006598
  
Biological name :SORL1
  
Synonyms : SORL1 / sortilin-related receptor
  
Possible biological names infered from orthology : O88307 / Q92673 / sortilin related receptor 1
  
Species: Gallus gallus
  
Chr. number: 24
Strand: -1
Band:
Gene start: 3488615
Gene end: 3526611
  
Corresponding Affymetrix probe sets: Gga.590.1.S1_at (Chicken Array)   GgaAffx.4102.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010625
Ensembl peptide - ENSGALP00000046461
NCBI entrez gene - 395998     See in Manteia.
RefSeq - NM_001305160
RefSeq - XM_015297961
RefSeq Peptide - NP_001292089
swissprot - E1BUD4
swissprot - A0A1D5P1C7
Ensembl - ENSGALG00000006598
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sorl1ENSDARG00000013892Danio rerio
 SORL1ENSG00000137642Homo sapiens
 Sorl1ENSMUSG00000049313Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SORCS3 / sortilin related VPS10 domain containing receptor 3 / Q8VI51* / Q9UPU3* / VPS10 domain-containing receptor SorCS3 *ENSGALG0000000843412
SORCS2 / sortilin related VPS10 domain containing receptor 2 / Q96PQ0* / Q9EPR5*ENSGALG0000001555412
SORCS1 / sortilin related VPS10 domain containing receptor 1 / Q8WY21*ENSGALG0000000846512
SORT1 / sortilin 1 / Q6PHU5* / Q99523* / Sortilin *ENSGALG000000335729


Protein motifs (from Interpro)
Interpro ID Name
 IPR000033  LDLR class B repeat
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR003961  Fibronectin type III
 IPR006581  VPS10
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013783  Immunoglobulin-like fold
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR031777  Sortilin, C-terminal
 IPR031778  Sortilin, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting IEA
 biological_processGO:0006622 protein targeting to lysosome IEA
 biological_processGO:0006892 post-Golgi vesicle-mediated transport IEA
 biological_processGO:0014910 regulation of smooth muscle cell migration IEA
 biological_processGO:0032091 negative regulation of protein binding IEA
 biological_processGO:0032460 negative regulation of protein oligomerization IEA
 biological_processGO:0034067 protein localization to Golgi apparatus IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 biological_processGO:0045053 protein retention in Golgi apparatus IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IEA
 biological_processGO:0050768 negative regulation of neurogenesis IEA
 biological_processGO:0051604 protein maturation IEA
 biological_processGO:0070863 positive regulation of protein exit from endoplasmic reticulum IEA
 biological_processGO:1901215 negative regulation of neuron death IEA
 biological_processGO:1902430 negative regulation of amyloid-beta formation IEA
 biological_processGO:1902771 positive regulation of choline O-acetyltransferase activity IEA
 biological_processGO:1902948 negative regulation of tau-protein kinase activity IEA
 biological_processGO:1902953 positive regulation of ER to Golgi vesicle-mediated transport IEA
 biological_processGO:1902955 positive regulation of early endosome to recycling endosome transport IEA
 biological_processGO:1902960 negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process IEA
 biological_processGO:1902963 negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process IEA
 biological_processGO:1902966 positive regulation of protein localization to early endosome IEA
 biological_processGO:1902997 negative regulation of neurofibrillary tangle assembly IEA
 biological_processGO:2001137 positive regulation of endocytic recycling IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005641 nuclear envelope lumen IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031985 Golgi cisterna IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0001540 amyloid-beta binding IEA
 molecular_functionGO:0030169 low-density lipoprotein particle binding IEA
 molecular_functionGO:0030306 ADP-ribosylation factor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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