ENSGALG00000007298


Gallus gallus

Features
Gene ID: ENSGALG00000007298
  
Biological name :BACE1
  
Synonyms : BACE1 / beta-secretase 1
  
Possible biological names infered from orthology : P56817 / P56818
  
Species: Gallus gallus
  
Chr. number: 24
Strand: -1
Band:
Gene start: 5238005
Gene end: 5244773
  
Corresponding Affymetrix probe sets: Gga.13835.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055878
Ensembl peptide - ENSGALP00000011801
NCBI entrez gene - 419768     See in Manteia.
RefSeq - XM_417908
RefSeq - XM_015298238
RefSeq - XM_015298239
RefSeq - XM_015298236
RefSeq - XM_015298237
swissprot - F1N916
swissprot - A0A1D5PSJ2
Ensembl - ENSGALG00000007298
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BACE1ENSDARG00000101716Danio rerio
 BACE1ENSG00000186318Homo sapiens
 Bace1ENSMUSG00000032086Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BACE2 / beta-site APP-cleaving enzyme 2 / Q9Y5Z0*ENSGALG0000003493246


Protein motifs (from Interpro)
Interpro ID Name
 IPR001461  Aspartic peptidase A1 family
 IPR001969  Aspartic peptidase, active site
 IPR009119  Beta-secretase BACE
 IPR009120  Beta-secretase BACE1
 IPR021109  Aspartic peptidase domain superfamily
 IPR032799  Xylanase inhibitor, C-terminal
 IPR033121  Peptidase family A1 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006509 membrane protein ectodomain proteolysis IEA
 biological_processGO:0030163 protein catabolic process IBA
 biological_processGO:0050435 amyloid-beta metabolic process IEA
 biological_processGO:0050804 modulation of chemical synaptic transmission IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005771 multivesicular body IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0001540 amyloid-beta binding IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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