ENSGALG00000034932


Gallus gallus

Features
Gene ID: ENSGALG00000034932
  
Biological name :BACE2
  
Synonyms : BACE2 / beta-site APP-cleaving enzyme 2
  
Possible biological names infered from orthology : Q9Y5Z0
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 108844363
Gene end: 108894770
  
Corresponding Affymetrix probe sets: GgaAffx.10287.1.S1_at (Chicken Array)   GgaAffx.10287.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048287
NCBI entrez gene - 418526     See in Manteia.
RefSeq - XM_015301191
swissprot - A0A1D5P6G1
Ensembl - ENSGALG00000034932
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bace2ENSDARG00000044781Danio rerio
 BACE2ENSG00000182240Homo sapiens
 Bace2ENSMUSG00000040605Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BACE1 / beta-secretase 1 / P56817* / P56818*ENSGALG0000000729836


Protein motifs (from Interpro)
Interpro ID Name
 IPR001461  Aspartic peptidase A1 family
 IPR001969  Aspartic peptidase, active site
 IPR009119  Beta-secretase BACE
 IPR009121  Beta-secretase BACE2
 IPR021109  Aspartic peptidase domain superfamily
 IPR033121  Peptidase family A1 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006509 membrane protein ectodomain proteolysis IEA
 biological_processGO:0042985 negative regulation of amyloid precursor protein biosynthetic process IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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