ENSDARG00000044781


Danio rerio

Features
Gene ID: ENSDARG00000044781
  
Biological name :bace2
  
Synonyms : bace2 / beta-site APP-cleaving enzyme 2
  
Possible biological names infered from orthology : Q9Y5Z0
  
Species: Danio rerio
  
Chr. number: 15
Strand: 1
Band:
Gene start: 6459847
Gene end: 6493615
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000065823
Ensembl peptide - ENSDARP00000127862
NCBI entrez gene - 449818     See in Manteia.
RefSeq - NM_001005991
RefSeq Peptide - NP_001005991
swissprot - F1QIH8
swissprot - Q5XJ89
swissprot - X1WCB9
ZFIN ID - ZDB-GENE-041010-68
Ensembl - ENSDARG00000044781
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BACE2ENSGALG00000034932Gallus gallus
 BACE2ENSG00000182240Homo sapiens
 Bace2ENSMUSG00000040605Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BACE1 / beta-secretase 1 / P56817*ENSDARG0000010171626


Protein motifs (from Interpro)
Interpro ID Name
 IPR001461  Aspartic peptidase A1 family
 IPR001969  Aspartic peptidase, active site
 IPR009119  Beta-secretase BACE
 IPR009120  Beta-secretase BACE1
 IPR009121  Beta-secretase BACE2
 IPR021109  Aspartic peptidase domain superfamily
 IPR033121  Peptidase family A1 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0030163 protein catabolic process IBA
 biological_processGO:0097324 melanocyte migration IMP
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004190 aspartic-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001115 trunk trunk neuromast increased amount , abnormal
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 ZFA:0009091 melanocyte melanocyte dilated , abnormal
Show

 ZFA:0009135 myelinating Schwann cell myelinating Schwann cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr