ENSGALG00000007443


Gallus gallus

Features
Gene ID: ENSGALG00000007443
  
Biological name :TMLHE
  
Synonyms : Q5F4B3 / TMLHE / Trimethyllysine dioxygenase, mitochondrial
  
Possible biological names infered from orthology : Q9NVH6 / trimethyllysine hydroxylase, epsilon
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 11050862
Gene end: 11066018
  
Corresponding Affymetrix probe sets: Gga.18010.1.S1_at (Chicken Array)   GgaAffx.4642.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012029
NCBI entrez gene - 422296     See in Manteia.
RefSeq - XM_015278284
RefSeq - NM_001012575
RefSeq - XM_015278282
RefSeq - XM_015278283
RefSeq Peptide - NP_001012593
swissprot - Q5F4B3
Ensembl - ENSGALG00000007443
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmlheENSDARG00000077547Danio rerio
 TMLHEENSG00000185973Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BBOX1 / gamma-butyrobetaine hydroxylase 1 / O75936* / Q924Y0* / Gamma-butyrobetaine dioxygenase *ENSGALG0000001329727


Protein motifs (from Interpro)
Interpro ID Name
 IPR003819  TauD/TfdA-like domain
 IPR010376  Gamma-butyrobetaine hydroxylase-like, N-terminal
 IPR012776  Trimethyllysine dioxygenase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045329 carnitine biosynthetic process ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050353 trimethyllysine dioxygenase activity ISS
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
Carnitine synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007443 TMLHE / Q5F4B3 / Trimethyllysine dioxygenase, mitochondrial / Q9NVH6* / trimethyllysine hydroxylase, epsilon*  / complex






 

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