ENSGALG00000007485


Gallus gallus

Features
Gene ID: ENSGALG00000007485
  
Biological name :TFRC
  
Synonyms : TFRC / transferrin receptor protein 1
  
Possible biological names infered from orthology : P02786 / Q62351 / transferrin receptor
  
Species: Gallus gallus
  
Chr. number: 9
Strand: 1
Band:
Gene start: 14984087
Gene end: 14998385
  
Corresponding Affymetrix probe sets: Gga.3619.1.S1_at (Chicken Array)   Gga.4193.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000012087
Ensembl peptide - ENSGALP00000050900
Ensembl peptide - ENSGALP00000045616
NCBI entrez gene - 396191     See in Manteia.
RefSeq - NM_205256
RefSeq - XM_015291382
RefSeq Peptide - NP_990587
swissprot - A0A1D5PDQ5
swissprot - A0A1D5NZ05
swissprot - F1NTM6
Ensembl - ENSGALG00000007485
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tfr1aENSDARG00000101322Danio rerio
 tfr1bENSDARG00000077372Danio rerio
 TFRCENSG00000072274Homo sapiens
 TfrcENSMUSG00000022797Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOLH1 / folate hydrolase 1 / O35409* / Q04609* / Glutamate carboxypeptidase 2 *ENSGALG0000001723424
NAALADL2 / N-acetylated alpha-linked acidic dipeptidase like 2 / Q58DX5*ENSGALG0000002367020


Protein motifs (from Interpro)
Interpro ID Name
 IPR003137  PA domain
 IPR007365  Transferrin receptor-like, dimerisation domain
 IPR007484  Peptidase M28
 IPR029513  Transferrin receptor protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0006898 receptor-mediated endocytosis IEA
 biological_processGO:0030316 osteoclast differentiation IEA
 biological_processGO:0030890 positive regulation of B cell proliferation IEA
 biological_processGO:0031623 receptor internalization IEA
 biological_processGO:0033572 transferrin transport IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0045780 positive regulation of bone resorption IEA
 biological_processGO:0045830 positive regulation of isotype switching IEA
 biological_processGO:0097286 iron ion import IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0055037 recycling endosome IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 cellular_componentGO:1990712 HFE-transferrin receptor complex IEA
 molecular_functionGO:0003725 double-stranded RNA binding IEA
 molecular_functionGO:0004998 transferrin receptor activity IEA
 molecular_functionGO:0033570 transferrin transmembrane transporter activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Golgi Associated Vesicle Biogenesis
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Transferrin endocytosis and recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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