ENSGALG00000008625


Gallus gallus

Features
Gene ID: ENSGALG00000008625
  
Biological name :ANAPC2
  
Synonyms : ANAPC2 / anaphase promoting complex subunit 2
  
Possible biological names infered from orthology : Q8BZQ7 / Q9UJX6
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 2280467
Gene end: 2289298
  
Corresponding Affymetrix probe sets: Gga.19872.1.S1_s_at (Chicken Array)   Gga.7685.1.S1_at (Chicken Array)   Gga.7685.2.S1_a_at (Chicken Array)   Gga.7685.3.S1_at (Chicken Array)   Gga.7685.3.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014037
Ensembl peptide - ENSGALP00000061380
NCBI entrez gene - 417258     See in Manteia.
RefSeq - XM_415533
swissprot - A0A1L1RRE7
swissprot - F1NLT0
Ensembl - ENSGALG00000008625
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 anapc2ENSDARG00000105035Danio rerio
 ANAPC2ENSG00000176248Homo sapiens
 Anapc2ENSMUSG00000026965Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001373  Cullin, N-terminal
 IPR011991  ArsR-like helix-turn-helix domain
 IPR014786  Anaphase-promoting complex subunit 2, C-terminal
 IPR016158  Cullin homology domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0031915 positive regulation of synaptic plasticity IEA
 biological_processGO:0070979 protein K11-linked ubiquitination IEA
 biological_processGO:0090129 positive regulation of synapse maturation IEA
 cellular_componentGO:0005680 anaphase-promoting complex IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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