ENSGALG00000009574


Gallus gallus

Features
Gene ID: ENSGALG00000009574
  
Biological name :IL12A
  
Synonyms : IL12A / interleukin-12 subunit alpha precursor
  
Possible biological names infered from orthology : interleukin 12A / P29459 / P43431
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 22362562
Gene end: 22364362
  
Corresponding Affymetrix probe sets: Gga.6437.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015585
NCBI entrez gene - 407090     See in Manteia.
RefSeq - NM_213588
RefSeq Peptide - NP_998753
swissprot - F1P2N3
Ensembl - ENSGALG00000009574
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL12AENSG00000168811Homo sapiens
 Il12aENSMUSG00000027776Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004281  Interleukin-12 alpha
 IPR009079  Four-helical cytokine-like, core


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001916 positive regulation of T cell mediated cytotoxicity IEA
 biological_processGO:0002860 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0010224 response to UV-B IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032609 interferon-gamma production IEA
 biological_processGO:0032700 negative regulation of interleukin-17 production IEA
 biological_processGO:0032729 positive regulation of interferon-gamma production IEA
 biological_processGO:0032816 positive regulation of natural killer cell activation IEA
 biological_processGO:0032946 positive regulation of mononuclear cell proliferation IEA
 biological_processGO:0034393 positive regulation of smooth muscle cell apoptotic process IEA
 biological_processGO:0035744 T-helper 1 cell cytokine production IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0042832 defense response to protozoan IEA
 biological_processGO:0045582 positive regulation of T cell differentiation IEA
 biological_processGO:0045785 positive regulation of cell adhesion IEA
 biological_processGO:0045954 positive regulation of natural killer cell mediated cytotoxicity IEA
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IEA
 biological_processGO:0050671 positive regulation of lymphocyte proliferation IEA
 biological_processGO:0050830 defense response to Gram-positive bacterium IEA
 biological_processGO:0051135 positive regulation of NK T cell activation IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0097191 extrinsic apoptotic signaling pathway IEA
 biological_processGO:0098586 cellular response to virus IEA
 biological_processGO:2000510 positive regulation of dendritic cell chemotaxis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0043514 interleukin-12 complex IEA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005143 interleukin-12 receptor binding IEA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0042163 interleukin-12 beta subunit binding IEA
 molecular_functionGO:0045513 interleukin-27 binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-35 Signalling
Interleukin-12 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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