ENSGALG00000011329


Gallus gallus

Features
Gene ID: ENSGALG00000011329
  
Biological name :AFDN
  
Synonyms : afadin, adherens junction formation factor / AFDN
  
Possible biological names infered from orthology : Afadin / P55196 / Q9QZQ1
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 42235566
Gene end: 42347326
  
Corresponding Affymetrix probe sets: Gga.12458.1.S1_s_at (Chicken Array)   Gga.8778.1.S1_at (Chicken Array)   GgaAffx.23525.1.S1_s_at (Chicken Array)   GgaAffx.23525.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053064
Ensembl peptide - ENSGALP00000048798
Ensembl peptide - ENSGALP00000055898
Ensembl peptide - ENSGALP00000018461
Ensembl peptide - ENSGALP00000049197
Ensembl peptide - ENSGALP00000048845
NCBI entrez gene - 421564     See in Manteia.
RefSeq - XM_015284360
RefSeq - XM_015284354
RefSeq - XM_015284355
RefSeq - XM_015284356
RefSeq - XM_015284357
RefSeq - XM_015284358
RefSeq - XM_015284359
RefSeq - XM_015284344
RefSeq - XM_015284345
RefSeq - XM_015284346
RefSeq - XM_015284347
RefSeq - XM_015284348
RefSeq - XM_015284349
RefSeq - XM_015284350
RefSeq - XM_015284351
RefSeq - XM_015284352
RefSeq - XM_015284353
swissprot - E1BYF5
swissprot - A0A1D5PSL2
swissprot - A0A1D5PJR8
swissprot - A0A1D5P8Z8
swissprot - A0A1D5P800
swissprot - A0A1D5P7V5
Ensembl - ENSGALG00000011329
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 afdnaENSDARG00000029472Danio rerio
 AFDNENSG00000130396Homo sapiens
 AfdnENSMUSG00000068036Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPP1R9BENSGALG000000423309
Q9ULJ8* / PPP1R9A* / protein phosphatase 1 regulatory subunit 9A* / protein phosphatase 1, regulatory (inhibitor) subunit 9A*ENSGALG000000096866
Q9ULJ8* / PPP1R9A* / protein phosphatase 1 regulatory subunit 9A* / protein phosphatase 1, regulatory (inhibitor) subunit 9A*ENSGALG000000452862


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000253  Forkhead-associated (FHA) domain
 IPR001478  PDZ domain
 IPR002710  Dilute domain
 IPR008984  SMAD/FHA domain superfamily
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0021537 telencephalon development IEA
 biological_processGO:0021987 cerebral cortex development IEA
 biological_processGO:0032880 regulation of protein localization IBA
 biological_processGO:0034332 adherens junction organization IBA
 biological_processGO:0034334 adherens junction maintenance IEA
 biological_processGO:0048854 brain morphogenesis IEA
 biological_processGO:0048872 homeostasis of number of cells IEA
 biological_processGO:0060019 radial glial cell differentiation IEA
 biological_processGO:0060563 neuroepithelial cell differentiation IEA
 biological_processGO:0070445 regulation of oligodendrocyte progenitor proliferation IEA
 biological_processGO:1902414 protein localization to cell junction IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0005913 cell-cell adherens junction IBA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0043296 apical junction complex IEA
 cellular_componentGO:0045177 apical part of cell IEA
 molecular_functionGO:0050839 cell adhesion molecule binding IBA


Pathways (from Reactome)
Pathway description
Adherens junctions interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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