ENSGALG00000011423


Gallus gallus

Features
Gene ID: ENSGALG00000011423
  
Biological name :FGFR1OP
  
Synonyms : FGFR1 oncogene partner / FGFR1OP
  
Possible biological names infered from orthology : FGFR1 onco partner / O95684 / Q66JX5
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 42625187
Gene end: 42644724
  
Corresponding Affymetrix probe sets: GgaAffx.7252.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018610
NCBI entrez gene - 421568     See in Manteia.
RefSeq - XM_004935549
RefSeq - XM_419609
swissprot - F1P288
Ensembl - ENSGALG00000011423
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgfr1opENSDARG00000003058Danio rerio
 O95684ENSG00000213066Homo sapiens
 Q66JX5ENSMUSG00000069135Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006594  LIS1 homology motif
 IPR018993  FGFR1 oncogene partner (FOP), N-terminal dimerisation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0034453 microtubule anchoring IEA
 biological_processGO:0061099 negative regulation of protein tyrosine kinase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030292 protein tyrosine kinase inhibitor activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr