ENSGALG00000011515


Gallus gallus

Features
Gene ID: ENSGALG00000011515
  
Biological name :ERCC3
  
Synonyms : ERCC3 / TFIIH basal transcription factor complex helicase XPB subunit
  
Possible biological names infered from orthology : ERCC excision repair 3, TFIIH core complex helicase subunit / P19447 / P49135
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 23753996
Gene end: 23770573
  
Corresponding Affymetrix probe sets: GgaAffx.12180.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018752
NCBI entrez gene - 424226     See in Manteia.
RefSeq - NM_001006523
RefSeq Peptide - NP_001006523
swissprot - F1NZ23
Ensembl - ENSGALG00000011515
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ercc3ENSDARG00000002402Danio rerio
 ERCC3ENSG00000163161Homo sapiens
 Ercc3ENSMUSG00000024382Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001161  Helicase XPB/Ssl2
 IPR001650  Helicase, C-terminal
 IPR006935  Helicase/UvrB, N-terminal
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032438  ERCC3/RAD25/XPB helicase, C-terminal domain
 IPR032830  Helicase XPB/Ssl2, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000717 nucleotide-excision repair, DNA duplex unwinding IEA
 biological_processGO:0006265 DNA topological change IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0008104 protein localization IEA
 biological_processGO:0009411 response to UV IEA
 biological_processGO:0009650 UV protection IEA
 biological_processGO:0033683 nucleotide-excision repair, DNA incision IEA
 biological_processGO:0035315 hair cell differentiation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:1901990 regulation of mitotic cell cycle phase transition IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005669 transcription factor TFIID complex IEA
 cellular_componentGO:0005675 holo TFIIH complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0008094 DNA-dependent ATPase activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008353 RNA polymerase II carboxy-terminal domain kinase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0043138 3"-5" DNA helicase activity IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
Formation of the Early Elongation Complex
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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