ENSGALG00000011623


Gallus gallus

Features
Gene ID: ENSGALG00000011623
  
Biological name :ADAMTS3
  
Synonyms : ADAM metallopeptidase with thrombospondin type 1 motif 3 / ADAMTS3
  
Possible biological names infered from orthology : a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3 / O15072
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 50807626
Gene end: 50937045
  
Corresponding Affymetrix probe sets: GgaAffx.21115.1.S1_at (Chicken Array)   GgaAffx.23613.1.S1_at (Chicken Array)   GgaAffx.7394.1.S1_at (Chicken Array)   GgaAffx.7394.1.S1_s_at (Chicken Array)   GgaAffx.7394.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000018965
Ensembl peptide - ENSGALP00000057230
Ensembl peptide - ENSGALP00000048204
NCBI entrez gene - 428760     See in Manteia.
RefSeq - XM_015276403
RefSeq - XM_015276404
swissprot - A0A1D5PW99
swissprot - A0A1D5P680
swissprot - F1NVD1
Ensembl - ENSGALG00000011623
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adamts3ENSDARG00000060127Danio rerio
 O15072ENSG00000156140Homo sapiens
 Adamts3ENSMUSG00000043635Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAMTS2 / ADAM metallopeptidase with thrombospondin type 1 motif 2 / O95450* / Q8C9W3* / A disintegrin and metalloproteinase with thrombospondin motifs 2 *ENSGALG0000003297457
ADAMTS14 / ADAM metallopeptidase with thrombospondin type 1 motif 14 / Q8WXS8* / a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14*ENSGALG0000003921955
ADAMTS18 / ADAM metallopeptidase with thrombospondin type 1 motif 18 / Q4VC17* / Q8TE60* / A disintegrin and metalloproteinase with thrombospondin motifs 18 *ENSGALG0000000534726
ADAMTS19 / ADAM metallopeptidase with thrombospondin type 1 motif 19 / P59509* / Q8TE59* / A disintegrin and metalloproteinase with thrombospondin motifs 19 *ENSGALG0000000015124
ADAMTS17 / ADAM metallopeptidase with thrombospondin type 1 motif 17 / Q8TE56* / a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17*ENSGALG0000003868824
ADAMTS6 / ADAM metallopeptidase with thrombospondin type 1 motif 6 / Q9UKP5* / a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6*ENSGALG0000001475120
ADAMTS10 / ADAM metallopeptidase with thrombospondin type 1 motif 10 / P58459* / Q9H324* / Mus musculus a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 ...ENSGALG0000003315720


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR002870  Peptidase M12B, propeptide
 IPR010294  ADAM-TS Spacer 1
 IPR010909  PLAC
 IPR024079  Metallopeptidase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0010573 vascular endothelial growth factor production IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0032964 collagen biosynthetic process IEA
 biological_processGO:1900748 positive regulation of vascular endothelial growth factor signaling pathway IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Collagen biosynthesis and modifying enzymes
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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