ENSGALG00000011932


Gallus gallus

Features
Gene ID: ENSGALG00000011932
  
Biological name :XRCC6
  
Synonyms : X-ray repair cross-complementing protein 5 precursor / XRCC6
  
Possible biological names infered from orthology : P12956 / X-ray repair complementing defective repair in Chinese hamster cells 6 / X-ray repair cross complementing 6
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 49591963
Gene end: 49606037
  
Corresponding Affymetrix probe sets: Gga.2738.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053314
Ensembl peptide - ENSGALP00000037185
NCBI entrez gene - 395767     See in Manteia.
RefSeq - NM_204927
RefSeq Peptide - NP_990258
swissprot - F1NED5
swissprot - A0A1D5PKF7
Ensembl - ENSGALG00000011932
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 xrcc6ENSDARG00000071551Danio rerio
 XRCC6ENSG00000196419Homo sapiens
 Xrcc6ENSMUSG00000022471Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR003034  SAP domain
 IPR005160  Ku70/Ku80 C-terminal arm
 IPR005161  Ku70/Ku80, N-terminal alpha/beta
 IPR006164  Ku70/Ku80 beta-barrel domain
 IPR006165  Ku70
 IPR016194  SPOC-like, C-terminal domain superfamily
 IPR027388  Ku70, bridge and pillars domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000723 telomere maintenance IEA
 biological_processGO:0002218 activation of innate immune response IEA
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0045860 positive regulation of protein kinase activity IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048660 regulation of smooth muscle cell proliferation IEA
 biological_processGO:0051290 protein heterotetramerization IEA
 biological_processGO:0071480 cellular response to gamma radiation IEA
 biological_processGO:0097680 double-strand break repair via classical nonhomologous end joining IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0032993 protein-DNA complex IEA
 cellular_componentGO:0043564 Ku70:Ku80 complex IEA
 cellular_componentGO:0070419 nonhomologous end joining complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003684 damaged DNA binding IEA
 molecular_functionGO:0003691 double-stranded telomeric DNA binding IEA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IEA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0030332 cyclin binding IEA
 molecular_functionGO:0042162 telomeric DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA
 molecular_functionGO:0051575 5"-deoxyribose-5-phosphate lyase activity IEA


Pathways (from Reactome)
Pathway description
Nonhomologous End-Joining (NHEJ)
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr