ENSGALG00000012834


Gallus gallus

Features
Gene ID: ENSGALG00000012834
  
Biological name :AKR1D1
  
Synonyms : AKR1D1 / aldo-keto reductase family 1 member D1
  
Possible biological names infered from orthology : 3-oxo-5-beta-steroid 4-dehydrogenase / P51857 / Q8VCX1
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 56606803
Gene end: 56640860
  
Corresponding Affymetrix probe sets: Gga.4536.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000020904
Ensembl peptide - ENSGALP00000063529
Ensembl peptide - ENSGALP00000061605
Ensembl peptide - ENSGALP00000060264
Ensembl peptide - ENSGALP00000048537
Ensembl peptide - ENSGALP00000045862
Ensembl peptide - ENSGALP00000045545
NCBI entrez gene - 418107     See in Manteia.
RefSeq - NM_001277393
RefSeq - XM_015285521
RefSeq Peptide - NP_001264322
swissprot - A0A1D5P753
swissprot - E1BU27
swissprot - A0A1D5NYT5
swissprot - A0A1D5NZP4
swissprot - A0A1L1RXG1
swissprot - A0A1L1RS22
Ensembl - ENSGALG00000012834
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AKR1D1ENSG00000122787Homo sapiens
 Akr1d1ENSMUSG00000038641Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AKR1B10L1 / aldo-keto reductase family 1, member B10 (aldose reductase) / Q9DCT1* / Akr1e1* / AKR1E2* / Q96JD6* / 1,5-anhydro-D-fructose reductase * / aldo-keto reductase family 1 member E2*ENSGALG0000004512251
AKR1E2 / aldo-keto reductase family 1, member B1-like / Q96JD6* / Akr1e1* / Q9DCT1* / 1,5-anhydro-D-fructose reductase * / aldo-keto reductase family 1 member E2*ENSGALG0000000346651
AKR1B10L2 / Q96JD6* / Akr1e1* / AKR1E2* / Q9DCT1* / 1,5-anhydro-D-fructose reductase * / aldo-keto reductase family 1 member E2*ENSGALG0000001307249
Q9DCT1* / Akr1e1* / AKR1E2* / Q96JD6* / 1,5-anhydro-D-fructose reductase * / aldo-keto reductase family 1 member E2*ENSGALG0000001928449
AKR1A1 / alcohol dehydrogenase / Q9JII6* / P14550* / Alcohol dehydrogenase [NADP(+)] * / aldo-keto reductase family 1 member A1*ENSGALG0000001024445
Q9DCT1* / Akr1e1* / AKR1E2* / Q96JD6* / 1,5-anhydro-D-fructose reductase * / aldo-keto reductase family 1 member E2*ENSGALG0000001305834


Protein motifs (from Interpro)
Interpro ID Name
 IPR018170  Aldo/keto reductase, conserved site
 IPR020471  Aldo/keto reductase
 IPR023210  NADP-dependent oxidoreductase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006699 bile acid biosynthetic process IEA
 biological_processGO:0006707 cholesterol catabolic process IEA
 biological_processGO:0007586 digestion IEA
 biological_processGO:0008207 C21-steroid hormone metabolic process IEA
 biological_processGO:0008209 androgen metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0047568 3-oxo-5-beta-steroid 4-dehydrogenase activity ISS


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Synthesis of bile acids and bile salts via 27-hydroxycholesterol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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