ENSGALG00000013218


Gallus gallus

Features
Gene ID: ENSGALG00000013218
  
Biological name :C3AR1
  
Synonyms : C3a anaphylatoxin chemotactic receptor / C3AR1
  
Possible biological names infered from orthology : complement C3a receptor 1 / O09047 / Q16581
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 66846831
Gene end: 66850139
  
Corresponding Affymetrix probe sets: GgaAffx.12851.1.S1_s_at (Chicken Array)   GgaAffx.8414.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053152
Ensembl peptide - ENSGALP00000021561
NCBI entrez gene - 418198     See in Manteia.
RefSeq - NM_001030769
RefSeq Peptide - NP_001025940
swissprot - F1NMA7
swissprot - A0A1D5PK03
Ensembl - ENSGALG00000013218
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU861476.1ENSDARG00000031749Danio rerio
 C3AR1ENSG00000171860Homo sapiens
 C3ar1ENSMUSG00000040552Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPR33 / G protein-coupled receptor 33 (gene/pseudogene) / O88416* / Q49SQ1* / Probable G-protein coupled receptor 33 *ENSGALG0000003088825
CMKLR1 / chemokine-like receptor 1 / P97468* / Q99788* / chemerin chemokine-like receptor 1* / Mus musculus chemokine-like receptor 1 (Cmklr1), transcript variant 1, mRNA.*ENSGALG0000003518224
GPR1 / G protein-coupled receptor 1 / P46091* / Q8K087*ENSGALG0000000858922


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000826  Formyl peptide receptor-related
 IPR001644  C3a anaphylatoxin chemotactic receptor
 IPR002234  Anaphylatoxin chemotactic receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002430 complement receptor mediated signaling pathway IEA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production IEA
 biological_processGO:0010759 positive regulation of macrophage chemotaxis IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0050900 leukocyte migration IBA
 biological_processGO:0060326 cell chemotaxis IBA
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004875 complement receptor activity IEA
 molecular_functionGO:0004876 complement component C3a receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (i) signalling events
Neutrophil degranulation
Regulation of Complement cascade
Anaphylatoxins initiate inflammatory responses


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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