ENSGALG00000013637


Gallus gallus

Features
Gene ID: ENSGALG00000013637
  
Biological name :TDP2
  
Synonyms : F1NW29 / TDP2 / Tyrosyl-DNA phosphodiesterase 2
  
Possible biological names infered from orthology : O95551 / Q9JJX7
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 90554824
Gene end: 90562107
  
Corresponding Affymetrix probe sets: GgaAffx.24237.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000064624
Ensembl peptide - ENSGALP00000022145
Ensembl peptide - ENSGALP00000061796
NCBI entrez gene - 421007     See in Manteia.
RefSeq - XM_015282387
RefSeq - NM_001276384
RefSeq Peptide - NP_001263313
swissprot - A0A1L1RSL2
swissprot - R4GF31
swissprot - F1NW29
Ensembl - ENSGALG00000013637
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tdp2aENSDARG00000069941Danio rerio
 tdp2bENSDARG00000035954Danio rerio
 TDP2ENSG00000111802Homo sapiens
 Tdp2ENSMUSG00000035958Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR009060  UBA-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006302 double-strand break repair ISS
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016235 aggresome IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0016605 PML body IEA
 molecular_functionGO:0000287 magnesium ion binding ISS
 molecular_functionGO:0003697 single-stranded DNA binding ISS
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding ISS
 molecular_functionGO:0036317 tyrosyl-RNA phosphodiesterase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070260 5"-tyrosyl-DNA phosphodiesterase activity ISS


Pathways (from Reactome)
Pathway description
Nonhomologous End-Joining (NHEJ)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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