ENSGALG00000013715


Gallus gallus

Features
Gene ID: ENSGALG00000013715
  
Biological name :DLC1
  
Synonyms : DLC1 / DLC1 Rho GTPase activating protein
  
Possible biological names infered from orthology : Q96QB1
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 64904550
Gene end: 64998990
  
Corresponding Affymetrix probe sets: GgaAffx.8737.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050159
Ensembl peptide - ENSGALP00000022258
NCBI entrez gene - 422740     See in Manteia.
RefSeq - XM_420693
RefSeq - XM_015285550
RefSeq - XM_015285551
RefSeq - XM_004936009
RefSeq - XM_004936011
swissprot - F1P3K3
swissprot - A0A1D5PBM9
Ensembl - ENSGALG00000013715
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dlc1ENSDARG00000079317Danio rerio
 DLC1ENSG00000164741Homo sapiens
 Dlc1ENSMUSG00000031523Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STARD8 / StAR related lipid transfer domain containing 8 / Q8K031* / Q92502* / StAR-related lipid transfer protein 8 *ENSGALG0000003241948
STARD13 / StAR related lipid transfer domain containing 13 / Q923Q2* / Q9Y3M8* / StAR-related lipid transfer protein 13 *ENSGALG0000001706529
ARHGAP18 / Rho GTPase activating protein 18 / Q8K0Q5* / Q8N392*ENSGALG0000003184313
ARHGAP40 / Rho GTPase activating protein 40 / E9Q6X9* / Q5TG30*ENSGALG0000000355011
ARHGAP6 / Rho GTPase activating protein 6 / O43182* / O54834*ENSGALG000000166029
ARHGAP28 / Rho GTPase activating protein 28 / Q8BN58* / Q9P2N2* / Mus musculus Rho GTPase activating protein 28 (Arhgap28), transcript variant 2, mRNA.*ENSGALG000000147589
ENSGALG000000071608
ARHGAP11A / rho GTPase-activating protein 11A / Q3KRB8* / Q6P4F7* / Q80Y19* / ARHGAP11B* / AC091057.5* / Rho GTPase activating protein 11B*ENSGALG000000097318
ENSGALG000000423397


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR001660  Sterile alpha motif domain
 IPR002913  START domain
 IPR008936  Rho GTPase activation protein
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR023393  START-like domain superfamily
 IPR028854  Rho GTPase-activating protein 7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035024 negative regulation of Rho protein signal transduction IEA
 biological_processGO:0035307 positive regulation of protein dephosphorylation IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051497 negative regulation of stress fiber assembly IEA
 biological_processGO:0051895 negative regulation of focal adhesion assembly IEA
 biological_processGO:1900119 positive regulation of execution phase of apoptosis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0042169 SH2 domain binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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