ENSGALG00000015256


Gallus gallus

Features
Gene ID: ENSGALG00000015256
  
Biological name :PAM
  
Synonyms : PAM / peptidylglycine alpha-amidating monooxygenase
  
Possible biological names infered from orthology : P19021 / P97467
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 50044582
Gene end: 50117715
  
Corresponding Affymetrix probe sets: Gga.17282.1.S1_at (Chicken Array)   GgaAffx.9717.1.S1_at (Chicken Array)   GgaAffx.9717.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024573
NCBI entrez gene - 427274     See in Manteia.
RefSeq - XM_015280468
RefSeq - XM_015280469
RefSeq - XM_015280470
RefSeq - XM_015280471
RefSeq - XM_015280472
RefSeq - XM_003643055
swissprot - F1NQN1
Ensembl - ENSGALG00000015256
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pamENSDARG00000100170Danio rerio
 PAMENSG00000145730Homo sapiens
 PamENSMUSG00000026335Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DBH / dopamine beta-hydroxylase / P09172* / Q64237* / Dopamine beta-hydroxylase Soluble dopamine beta-hydroxylase*ENSGALG0000004004511
MOXD1 / DBH-like monooxygenase protein 1 precursor / Q6UVY6* / Q9CXI3* / monooxygenase DBH like 1* / DBH-like monooxygenase protein 1 *ENSGALG0000000291110


Protein motifs (from Interpro)
Interpro ID Name
 IPR000323  Copper type II, ascorbate-dependent monooxygenase, N-terminal
 IPR000720  Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase
 IPR001258  NHL repeat
 IPR008977  PHM/PNGase F domain superfamily
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013017  NHL repeat, subgroup
 IPR014783  Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-2 conserved site
 IPR014784  Copper type II, ascorbate-dependent monooxygenase-like, C-terminal
 IPR020611  Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved site
 IPR024548  Copper type II ascorbate-dependent monooxygenase, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001519 peptide amidation IEA
 biological_processGO:0006518 peptide metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004504 peptidylglycine monooxygenase activity IEA
 molecular_functionGO:0004598 peptidylamidoglycolate lyase activity IEA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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