ENSGALG00000017272


Gallus gallus

Features
Gene ID: ENSGALG00000017272
  
Biological name :VWF
  
Synonyms : Gallus gallus von Willebrand factor (VWF), mRNA. / VWF
  
Possible biological names infered from orthology : P04275 / von Willebrand factor
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 74316620
Gene end: 74458552
  
Corresponding Affymetrix probe sets: Gga.10952.1.S1_s_at (Chicken Array)   GgaAffx.25229.1.S1_at (Chicken Array)   GgaAffx.25230.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027871
Ensembl peptide - ENSGALP00000053825
Ensembl peptide - ENSGALP00000048505
Ensembl peptide - ENSGALP00000036463
NCBI entrez gene - 419031     See in Manteia.
RefSeq - XM_417223
RefSeq - NM_001318464
RefSeq - XM_004938077
RefSeq Peptide - NP_001305393
swissprot - A0A1D5P722
swissprot - E1C6J4
swissprot - E1C4Z6
swissprot - A0A1D5PLV4
Ensembl - ENSGALG00000017272
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vwfENSDARG00000077231Danio rerio
 VWFENSG00000110799Homo sapiens
 VwfENSMUSG00000001930Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SSPO / SCO-spondin precursor / Q8CG65* / SCO-spondin*ENSGALG0000003341722
ENSGALG0000003895022
OTOGL / otogelin like / F7A4A7* / Q3ZCN5* / Otogelin-like protein *ENSGALG0000001034221
ovomucin precursor / MUC5B* / Q9HC84* / MUC5AC* / P98088* / mucin 5B, oligomeric mucus/gel-forming* / mucin 5AC, oligomeric mucus/gel-forming*ENSGALG0000000671721
OTOG / otogelin / Q6ZRI0*ENSGALG0000000620819
MUC5B* / Q9HC84* / MUC5AC* / P98088* / mucin 5B, oligomeric mucus/gel-forming* / mucin 5AC, oligomeric mucus/gel-forming*ENSGALG0000003173716
TECTA / tectorin alpha / O08523* / O75443*ENSGALG0000004085714
MUC6 / mucin 6, oligomeric mucus/gel-forming / Q6W4X9* / mucin-6 *ENSGALG0000004053014
MUC5B* / Q9HC84* / MUC5AC* / P98088* / mucin 5B, oligomeric mucus/gel-forming* / mucin 5AC, oligomeric mucus/gel-forming*ENSGALG0000003414414
ZAN* / zonadhesin* / zonadhesin (gene/pseudogene)*ENSGALG0000004139214
ENSGALG0000003591410
ENSGALG000000439735
ENSGALG000000461525
ENSGALG000000410385


Protein motifs (from Interpro)
Interpro ID Name
 IPR001007  VWFC domain
 IPR001846  von Willebrand factor, type D domain
 IPR002035  von Willebrand factor, type A
 IPR002919  Trypsin Inhibitor-like, cysteine rich domain
 IPR006207  Cystine knot, C-terminal
 IPR014853  Uncharacterised domain, cysteine-rich
 IPR032361  von Willebrand factor, VWA N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0007599 hemostasis IEA
 biological_processGO:0030168 platelet activation IEA
 biological_processGO:0031589 cell-substrate adhesion IEA
 biological_processGO:0051260 protein homooligomerization IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0033093 Weibel-Palade body IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005518 collagen binding IEA
 molecular_functionGO:0019865 immunoglobulin binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA
 molecular_functionGO:0051087 chaperone binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Intrinsic Pathway of Fibrin Clot Formation
Integrin cell surface interactions
Integrin alphaIIb beta3 signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
p130Cas linkage to MAPK signaling for integrins
GP1b-IX-V activation signalling
MAP2K and MAPK activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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