ENSGALG00000026225


Gallus gallus

Features
Gene ID: ENSGALG00000026225
  
Biological name :PSMD12
  
Synonyms : 26S proteasome non-ATPase regulatory subunit 12 / PSMD12
  
Possible biological names infered from orthology : O00232 / proteasome 26S subunit, non-ATPase 12 / proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 / Q9D8W5
  
Species: Gallus gallus
  
Chr. number: 18
Strand: 1
Band:
Gene start: 7207510
Gene end: 7215519
  
Corresponding Affymetrix probe sets: GgaAffx.2313.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000041149
Ensembl peptide - ENSGALP00000059727
Ensembl peptide - ENSGALP00000058760
NCBI entrez gene - 417425     See in Manteia.
RefSeq - NM_001030706
RefSeq Peptide - NP_001025877
swissprot - A0A1L1RLT1
swissprot - A0A1L1RJ37
swissprot - F1NPQ0
Ensembl - ENSGALG00000026225
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 psmd12ENSDARG00000052377Danio rerio
 O00232ENSG00000197170Homo sapiens
 Psmd12ENSMUSG00000020720Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR011991  ArsR-like helix-turn-helix domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005838 proteasome regulatory particle IEA
 cellular_componentGO:0008541 proteasome regulatory particle, lid subcomplex IBA
 cellular_componentGO:0022624 proteasome accessory complex IEA
 cellular_componentGO:0031595 nuclear proteasome complex IBA


Pathways (from Reactome)
Pathway description
Activation of NF-kappaB in B cells
Cross-presentation of soluble exogenous antigens (endosomes)
Autodegradation of Cdh1 by Cdh1:APC/C
SCF-beta-TrCP mediated degradation of Emi1
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
SCF(Skp2)-mediated degradation of p27/p21
Degradation of beta-catenin by the destruction complex
Downstream TCR signaling
Separation of Sister Chromatids
FCERI mediated NF-kB activation
Autodegradation of the E3 ubiquitin ligase COP1
Regulation of ornithine decarboxylase (ODC)
ABC-family proteins mediated transport
AUF1 (hnRNP D0) binds and destabilizes mRNA
Asymmetric localization of PCP proteins
Degradation of AXIN
Degradation of DVL
Hedgehog ligand biogenesis
CLEC7A (Dectin-1) signaling
Degradation of GLI1 by the proteasome
GLI3 is processed to GLI3R by the proteasome
Hedgehog on state
Regulation of RAS by GAPs
TNFR2 non-canonical NF-kB pathway
MAPK6/MAPK4 signaling
UCH proteinases
Ub-specific processing proteases
Neutrophil degranulation
CDT1 association with the CDC6:ORC:origin complex
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
Ubiquitin-dependent degradation of Cyclin D1
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Regulation of RUNX2 expression and activity
Regulation of RUNX3 expression and activity
Regulation of PTEN stability and activity
Neddylation
Interleukin-1 signaling
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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