ENSGALG00000040005


Gallus gallus

Features
Gene ID: ENSGALG00000040005
  
Biological name :PPP2R5D
  
Synonyms : PPP2R5D / protein phosphatase 2 regulatory subunit Bdelta
  
Possible biological names infered from orthology : protein phosphatase 2, regulatory subunit B, delta / Q14738
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 4257291
Gene end: 4277899
  
Corresponding Affymetrix probe sets: Gga.19338.1.S1_at (Chicken Array)   GgaAffx.5380.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050771
swissprot - A0A1D5PDC7
Ensembl - ENSGALG00000040005
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp2r5dENSDARG00000014428Danio rerio
 Q14738ENSG00000112640Homo sapiens
 Ppp2r5dENSMUSG00000059409Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPP2R5C / serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform / Q13362* / Q60996* / protein phosphatase 2 regulatory subunit Bgamma* / protein phosphatase 2, re...ENSGALG0000002999680
PPP2R5E / protein phosphatase 2 regulatory subunit Bepsilon / Q16537* / Q61151* / protein phosphatase 2, regulatory subunit B, epsilon*ENSGALG0000001184058
PPP2R5A / protein phosphatase 2 regulatory subunit Balpha / Q15172* / Q6PD03* / protein phosphatase 2, regulatory subunit B, alpha*ENSGALG0000000982858
ENSGALG0000004607129


Protein motifs (from Interpro)
Interpro ID Name
 IPR002554  Protein phosphatase 2A, regulatory B subunit, B56
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0035307 positive regulation of protein dephosphorylation IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
DARPP-32 events
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
ERK/MAPK targets
ERKs are inactivated
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
CTLA4 inhibitory signaling
Disassembly of the destruction complex and recruitment of AXIN to the membrane
RHO GTPases Activate Formins
RAF activation
Negative regulation of MAPK pathway
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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