ENSGALG00000041422


Gallus gallus

Features
Gene ID: ENSGALG00000041422
  
Biological name :EGLN1
  
Synonyms : egl-9 family hypoxia inducible factor 1 / EGLN1
  
Possible biological names infered from orthology : Egl nine homolog 1 / Q91YE3 / Q9GZT9
  
Species: Gallus gallus
  
Chr. number: 3
Strand: 1
Band:
Gene start: 39857052
Gene end: 39884582
  
Corresponding Affymetrix probe sets: Gga.5705.1.S1_at (Chicken Array)   GgaAffx.23433.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056238
NCBI entrez gene - 768374     See in Manteia.
RefSeq - XM_015284393
swissprot - A0A1D5PTJ0
Ensembl - ENSGALG00000041422
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 egln1aENSDARG00000038996Danio rerio
 egln1bENSDARG00000105156Danio rerio
 egln1bENSDARG00000004632Danio rerio
 EGLN1ENSG00000135766Homo sapiens
 Egln1ENSMUSG00000031987Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EGLN3 / egl-9 family hypoxia inducible factor 3 / Q9H6Z9*ENSGALG0000001000172


Protein motifs (from Interpro)
Interpro ID Name
 IPR005123  Oxoglutarate/iron-dependent dioxygenase
 IPR006620  Prolyl 4-hydroxylase, alpha subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline IEA
 biological_processGO:0032364 oxygen homeostasis IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity IEA
 biological_processGO:0045765 regulation of angiogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0055008 cardiac muscle tissue morphogenesis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060347 heart trabecula formation IEA
 biological_processGO:0060412 ventricular septum morphogenesis IEA
 biological_processGO:0060711 labyrinthine layer development IEA
 biological_processGO:0071731 response to nitric oxide IEA
 biological_processGO:1901214 regulation of neuron death IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors IEA
 molecular_functionGO:0031418 L-ascorbic acid binding IEA
 molecular_functionGO:0031545 peptidyl-proline 4-dioxygenase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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