ENSGALG00000042184


Gallus gallus

Features
Gene ID: ENSGALG00000042184
  
Biological name :ALDH4A1
  
Synonyms : aldehyde dehydrogenase 4 family member A1 / ALDH4A1
  
Possible biological names infered from orthology : Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial / P30038 / Q8CHT0
  
Species: Gallus gallus
  
Chr. number: 21
Strand: -1
Band:
Gene start: 4544396
Gene end: 4552069
  
Corresponding Affymetrix probe sets: Gga.7008.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045434
Ensembl peptide - ENSGALP00000057676
NCBI entrez gene - 419467     See in Manteia.
RefSeq - NM_001252104
RefSeq Peptide - NP_001239033
swissprot - A0A1D5PXI1
swissprot - A0A1D5NYH6
Ensembl - ENSGALG00000042184
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aldh4a1ENSDARG00000038207Danio rerio
 P30038ENSG00000159423Homo sapiens
 Q8CHT0ENSMUSG00000028737Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005931  Delta-1-pyrroline-5-carboxylate dehydrogenase
 IPR015590  Aldehyde dehydrogenase domain
 IPR016160  Aldehyde dehydrogenase, cysteine active site
 IPR016161  Aldehyde/histidinol dehydrogenase
 IPR016162  Aldehyde dehydrogenase, N-terminal
 IPR016163  Aldehyde dehydrogenase, C-terminal
 IPR029510  Aldehyde dehydrogenase, glutamic acid active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0010133 proline catabolic process to glutamate IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity IEA
 molecular_functionGO:0004029 aldehyde dehydrogenase (NAD) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Proline catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000042184 ALDH4A1 / aldehyde dehydrogenase 4 family member A1 / P30038* / Q8CHT0* / Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial *  / complex






 

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contact: otassy@igbmc.fr