ENSGALG00000042878


Gallus gallus

Features
Gene ID: ENSGALG00000042878
  
Biological name :PTH
  
Synonyms : P15743 / Parathyroid hormone / PTH
  
Possible biological names infered from orthology : P01270
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 7527397
Gene end: 7531465
  
Corresponding Affymetrix probe sets: Gga.78.1.A1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044567
NCBI entrez gene - 396436     See in Manteia.
RefSeq - NM_205452
RefSeq Peptide - NP_990783
swissprot - A9YX65
swissprot - P15743
Ensembl - ENSGALG00000042878
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTHENSG00000152266Homo sapiens
 PthENSMUSG00000059077Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001415  Parathyroid hormone/parathyroid hormone-related protein
 IPR003625  Parathyroid hormone


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007202 activation of phospholipase C activity IEA
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030501 positive regulation of bone mineralization IEA
 biological_processGO:0030819 obsolete positive regulation of cAMP biosynthetic process IEA
 biological_processGO:0034645 cellular macromolecule biosynthetic process IEA
 biological_processGO:0045725 positive regulation of glycogen biosynthetic process IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046326 positive regulation of glucose import IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0060732 positive regulation of inositol phosphate biosynthetic process IEA
 biological_processGO:0071864 positive regulation of cell proliferation in bone marrow IEA
 biological_processGO:0071866 negative regulation of apoptotic process in bone marrow IEA
 biological_processGO:0090290 positive regulation of osteoclast proliferation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005623 cell IEA
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0005179 hormone activity IBA
 molecular_functionGO:0031856 parathyroid hormone receptor binding IBA
 molecular_functionGO:0031857 type 1 parathyroid hormone receptor binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA
 molecular_functionGO:0048018 receptor ligand activity IEA
 molecular_functionGO:0051428 peptide hormone receptor binding IEA


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005476 PTH1R / parathyroid hormone 1 receptor / P41593* / Q03431* / Parathyroid hormone/parathyroid hormone-related peptide receptor *  / reaction / complex






 

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