ENSMUSG00000001155


Mus musculus

Features
Gene ID: ENSMUSG00000001155
  
Biological name :Ftcd
  
Synonyms : Formimidoyltransferase-cyclodeaminase Glutamate formimidoyltransferase Formimidoyltetrahydrofolate cyclodeaminase / Ftcd / Q91XD4
  
Possible biological names infered from orthology : E5RQL4 / formimidoyltransferase cyclodeaminase / formiminotransferase cyclodeaminase N-terminal like / FTCDNL1 / O95954
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 76575648
Gene end: 76590338
  
Corresponding Affymetrix probe sets: 10364222 (MoGene1.0st)   1419670_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001183
NCBI entrez gene - 14317     See in Manteia.
MGI - MGI:1339962
RefSeq - XM_006513216
RefSeq - NM_080845
RefSeq - XM_006513215
RefSeq Peptide - NP_543121
swissprot - Q91XD4
Ensembl - ENSMUSG00000001155
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:153901ENSDARG00000062423Danio rerio
 FTCDENSGALG00000006131Gallus gallus
 E5RQL4ENSG00000226124Homo sapiens
 FTCDENSG00000160282Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004227  Formiminotransferase catalytic domain
 IPR007044  Cyclodeaminase/cyclohydrolase
 IPR012886  Formiminotransferase, N-terminal subdomain
 IPR013802  Formiminotransferase, C-terminal subdomain
 IPR022384  Formiminotransferase catalytic domain superfamily
 IPR036178  Formimidoyltransferase-cyclodeaminase-like superfamily
 IPR037064  Formiminotransferase, N-terminal subdomain superfamily
 IPR037070  Formiminotransferase, C-terminal subdomain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006547 histidine metabolic process IEA
 biological_processGO:0006548 histidine catabolic process TAS
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0019556 histidine catabolic process to glutamate and formamide IEA
 biological_processGO:0019557 histidine catabolic process to glutamate and formate IEA
 biological_processGO:0035999 tetrahydrofolate interconversion IEA
 biological_processGO:0044237 cellular metabolic process IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0030868 smooth endoplasmic reticulum membrane ISO
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005542 folic acid binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0030407 formimidoyltransferase activity IEA
 molecular_functionGO:0030409 glutamate formimidoyltransferase activity TAS
 molecular_functionGO:0030412 formimidoyltetrahydrofolate cyclodeaminase activity TAS


Pathways (from Reactome)
Pathway description
Histidine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001155 Ftcd / Q91XD4 / Formimidoyltransferase-cyclodeaminase Glutamate formimidoyltransferase Formimidoyltetrahydrofolate cyclodeaminase / E5RQL4* / O95954* / FTCDNL1* / formimidoyltransferase cyc...  / complex






 

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