ENSMUSG00000002733


Mus musculus

Features
Gene ID: ENSMUSG00000002733
  
Biological name :Plekha3
  
Synonyms : Pleckstrin homology domain-containing family A member 3 / Plekha3 / Q9ERS4
  
Possible biological names infered from orthology : pleckstrin homology domain containing A3 / Q9HB20
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: C3
Gene start: 76675281
Gene end: 76696828
  
Corresponding Affymetrix probe sets: 10473097 (MoGene1.0st)   1420839_at (Mouse Genome 430 2.0 Array)   1420840_at (Mouse Genome 430 2.0 Array)   1447772_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000107551
NCBI entrez gene - 83435     See in Manteia.
MGI - MGI:1932515
RefSeq - NM_031256
RefSeq - XM_006500446
RefSeq Peptide - NP_112546
swissprot - Q9ERS4
Ensembl - ENSMUSG00000002733
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plekha3ENSDARG00000056601Danio rerio
 PLEKHA3ENSGALG00000009135Gallus gallus
 Q9HB20ENSG00000116095Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80W71 / Plekha8 / Pleckstrin homology domain-containing family A member 8 / Q96JA3* / pleckstrin homology domain containing A8*ENSMUSG0000000522548
Q9EQG9 / Col4a3bp / Collagen type IV alpha-3-binding protein / Q9Y5P4*ENSMUSG0000002166927


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
Show

Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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