ENSMUSG00000005225


Mus musculus

Features
Gene ID: ENSMUSG00000005225
  
Biological name :Plekha8
  
Synonyms : Pleckstrin homology domain-containing family A member 8 / Plekha8 / Q80W71
  
Possible biological names infered from orthology : pleckstrin homology domain containing A8 / Q96JA3
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: B3
Gene start: 54595111
Gene end: 54645839
  
Corresponding Affymetrix probe sets: 10538394 (MoGene1.0st)   1436128_at (Mouse Genome 430 2.0 Array)   1454819_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000098935
Ensembl peptide - ENSMUSP00000112466
NCBI entrez gene - 231999     See in Manteia.
MGI - MGI:2681164
RefSeq - NM_001001335
RefSeq - NM_001164361
RefSeq Peptide - NP_001001335
RefSeq Peptide - NP_001157833
swissprot - Q80W71
Ensembl - ENSMUSG00000005225
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plekha8ENSDARG00000040698Danio rerio
 PLEKHA8ENSGALG00000011185Gallus gallus
 Q96JA3ENSG00000106086Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9ERS4 / Plekha3 / Pleckstrin homology domain-containing family A member 3 / Q9HB20* / pleckstrin homology domain containing A3*ENSMUSG0000000273328
Q9EQG9 / Col4a3bp / Collagen type IV alpha-3-binding protein / Q9Y5P4*ENSMUSG0000002166918


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR014830  Glycolipid transfer protein domain
 IPR036497  Glycolipid transfer protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport ISO
 biological_processGO:0035621 ER to Golgi ceramide transport ISO
 biological_processGO:0046836 glycolipid transport IEA
 biological_processGO:0120009 intermembrane lipid transfer IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005802 trans-Golgi network ISO
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0017089 glycolipid transporter activity ISO
 molecular_functionGO:0051861 glycolipid binding ISS
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding ISS
 molecular_functionGO:0097001 ceramide binding ISS
 molecular_functionGO:0120013 intermembrane lipid transfer activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002631 abnormal epididymis morphology "malformation of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

 MP:0004931 enlarged epididymis "increase in the average size of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pik3c2atm1b(EUCOMM)Hmgu/Pik3c2a+
Genetic Background: C57BL/6N-Pik3c2atm1b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr