ENSG00000106086


Homo sapiens

Features
Gene ID: ENSG00000106086
  
Biological name :PLEKHA8
  
Synonyms : pleckstrin homology domain containing A8 / PLEKHA8 / Q96JA3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p14.3
Gene start: 30027404
Gene end: 30130483
  
Corresponding Affymetrix probe sets: 1560556_a_at (Human Genome U133 Plus 2.0 Array)   220157_x_at (Human Genome U133 Plus 2.0 Array)   224208_at (Human Genome U133 Plus 2.0 Array)   227247_at (Human Genome U133 Plus 2.0 Array)   231543_at (Human Genome U133 Plus 2.0 Array)   232212_at (Human Genome U133 Plus 2.0 Array)   233943_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000397947
Ensembl peptide - ENSP00000379558
Ensembl peptide - ENSP00000407802
Ensembl peptide - ENSP00000484427
Ensembl peptide - ENSP00000258679
Ensembl peptide - ENSP00000379556
NCBI entrez gene - 84725     See in Manteia.
OMIM - 608639
RefSeq - XM_017012749
RefSeq - XM_011515592
RefSeq - XM_011515594
RefSeq - XM_011515595
RefSeq - XM_011515596
RefSeq - XM_017012744
RefSeq - XM_017012745
RefSeq - XM_017012746
RefSeq - XM_017012747
RefSeq - XM_017012748
RefSeq - NM_001197026
RefSeq - NM_001197027
RefSeq - NM_001350974
RefSeq - NM_032639
RefSeq - XM_005249897
RefSeq - XM_011515591
RefSeq Peptide - NP_116028
RefSeq Peptide - NP_001183955
RefSeq Peptide - NP_001183956
RefSeq Peptide - NP_001337902
RefSeq Peptide - NP_001337903
swissprot - Q96JA3
swissprot - J3KQS5
swissprot - B5MDU3
swissprot - A0A087X1S6
Ensembl - ENSG00000106086
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plekha8ENSDARG00000040698Danio rerio
 PLEKHA8ENSGALG00000011185Gallus gallus
 Q80W71ENSMUSG00000005225Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9HB20 / PLEKHA3 / pleckstrin homology domain containing A3ENSG0000011609528
Q9Y5P4 / COL4A3BP / collagen type IV alpha 3 binding proteinENSG0000011316318


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR014830  Glycolipid transfer protein domain
 IPR036497  Glycolipid transfer protein superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006661 phosphatidylinositol biosynthetic process TAS
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0035621 ER to Golgi ceramide transport IDA
 biological_processGO:0046836 glycolipid transport IEA
 biological_processGO:0120009 intermembrane lipid transfer IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0017089 glycolipid transporter activity IDA
 molecular_functionGO:0051861 glycolipid binding IDA
 molecular_functionGO:0070273 phosphatidylinositol-4-phosphate binding IDA
 molecular_functionGO:0097001 ceramide binding IDA
 molecular_functionGO:0120013 intermembrane lipid transfer activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143761 ARF1 / P84077 / ADP ribosylation factor 1  / complex / reaction






 

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