ENSMUSG00000003166


Mus musculus

Features
Gene ID: ENSMUSG00000003166
  
Biological name :Dgcr2
  
Synonyms : Dgcr2
  
Possible biological names infered from orthology : DiGeorge syndrome critical region gene 2 / P98153
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A3
Gene start: 17839482
Gene end: 17894145
  
Corresponding Affymetrix probe sets: 10438232 (MoGene1.0st)   1421809_at (Mouse Genome 430 2.0 Array)   1421810_at (Mouse Genome 430 2.0 Array)   1435276_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112783
Ensembl peptide - ENSMUSP00000113506
Ensembl peptide - ENSMUSP00000012152
Ensembl peptide - ENSMUSP00000064603
NCBI entrez gene - 13356     See in Manteia.
MGI - MGI:892866
RefSeq - NM_001109750
RefSeq - NM_010048
RefSeq Peptide - NP_001103220
RefSeq Peptide - NP_034178
swissprot - Q8C2R4
swissprot - A0A0R4J1M6
swissprot - Q6P5A9
swissprot - E9QNU3
Ensembl - ENSMUSG00000003166
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dgcr2ENSDARG00000042962Danio rerio
 DGCR2ENSGALG00000005891Gallus gallus
 DGCR2ENSG00000070413Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm20518 / DGCR2* / P98153* / DiGeorge syndrome critical region gene 2*ENSMUSG0000009247099


Protein motifs (from Interpro)
Interpro ID Name
 IPR001007  VWFC domain
 IPR001304  C-type lectin-like
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR034010  DGCR2-like, C-type lectin-like domain
 IPR036055  LDL receptor-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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