ENSMUSG00000003824


Mus musculus

Features
Gene ID: ENSMUSG00000003824
  
Biological name :Syce2
  
Synonyms : Q505B8 / Syce2 / Synaptonemal complex central element protein 2
  
Possible biological names infered from orthology : Q6PIF2
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C3
Gene start: 84872111
Gene end: 84888221
  
Corresponding Affymetrix probe sets: 10573451 (MoGene1.0st)   1429270_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003922
Ensembl peptide - ENSMUSP00000122159
Ensembl peptide - ENSMUSP00000131438
NCBI entrez gene - 71846     See in Manteia.
MGI - MGI:1919096
RefSeq - NM_001168244
RefSeq - NM_001168246
RefSeq - NM_027954
RefSeq Peptide - NP_082230
RefSeq Peptide - NP_001161716
RefSeq Peptide - NP_001161718
swissprot - Q505B8
swissprot - F8WHI9
swissprot - E9PYH4
Ensembl - ENSMUSG00000003824
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syce2ENSDARG00000103187Danio rerio
 SYCE2ENSG00000161860Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR034609  Synaptonemal complex central element protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007130 synaptonemal complex assembly IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0000795 synaptonemal complex ISS
 cellular_componentGO:0000801 central element IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
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Allelic Composition: Spo11tm1Mjn/Spo11tm1Mjn
Genetic Background: involves: 129X1/SvJ * C57BL/6JOlaHsd

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0005168 abnormal female meiosis "malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Thtm1Srt/Thtm1Srt
Genetic Background: involves: 129S2/SvPas * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000078938 Syce3 / B5KM66 / Synaptonemal complex central element protein 3 / A1L190*  / complex
 ENSMUSG00000032065 Tex12 / Q9CR81 / Testis-expressed protein 12 / Q9BXU0* / testis expressed 12*  / complex
 ENSMUSG00000025480 Syce1 / Q9D495 / Synaptonemal complex central element protein 1 / Q8N0S2*  / complex






 

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contact: otassy@igbmc.fr