ENSMUSG00000078938


Mus musculus

Features
Gene ID: ENSMUSG00000078938
  
Biological name :Syce3
  
Synonyms : B5KM66 / Syce3 / Synaptonemal complex central element protein 3
  
Possible biological names infered from orthology : A1L190
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E3
Gene start: 89390174
Gene end: 89410503
  
Corresponding Affymetrix probe sets: 1435412_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000104937
Ensembl peptide - ENSMUSP00000131766
NCBI entrez gene - 75459     See in Manteia.
MGI - MGI:1922709
RefSeq - NM_001162880
RefSeq - NM_001162882
RefSeq Peptide - NP_001156352
RefSeq Peptide - NP_001156354
swissprot - E7D6R1
swissprot - B5KM66
Ensembl - ENSMUSG00000078938
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:194246ENSDARG00000092889Danio rerio
 SYCE3ENSGALG00000042936Gallus gallus
 SYCE3ENSG00000217442Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR028145  Synaptonemal complex central element protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007130 synaptonemal complex assembly IMP
 biological_processGO:0007131 reciprocal meiotic recombination IMP
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0043065 positive regulation of apoptotic process IDA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0000801 central element IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001126 abnormal ovary morphology "malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0001127 small ovary "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0001132 absent mature ovarian follicles "failure of ovarian follicle differentiation" [J:35782]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0001930 abnormal meiosis "malfunction in the process of nuclear division that results in gametes with one half the normal number of the original cell" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0005168 abnormal female meiosis "malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0009451 abnormal chromosome pairing during meiosis "an anomaly in the highly specific side-by-side association of homologous chromosomes during first prophase of meiosis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

 MP:0009452 abnormal synaptonemal complex "an anomaly in the formation of the proteinaceous structure involved in the pairing of homologous chromosomes during first prophase of meiosis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cd79am1Anu/Cd79am1Anu
Genetic Background: C57BL/6-Cd79am1Anu

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003824 Syce2 / Q505B8 / Synaptonemal complex central element protein 2 / Q6PIF2*  / complex
 ENSMUSG00000025480 Syce1 / Q9D495 / Synaptonemal complex central element protein 1 / Q8N0S2*  / complex
 ENSMUSG00000032065 Tex12 / Q9CR81 / Testis-expressed protein 12 / Q9BXU0* / testis expressed 12*  / complex






 

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