ENSMUSG00000004233


Mus musculus

Features
Gene ID: ENSMUSG00000004233
  
Biological name :Wars2
  
Synonyms : Q9CYK1 / tryptophanyl tRNA synthetase 2 (mitochondrial) / Wars2
  
Possible biological names infered from orthology : Q9UGM6
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.2
Gene start: 99141068
Gene end: 99239186
  
Corresponding Affymetrix probe sets: 10494664 (MoGene1.0st)   1429279_at (Mouse Genome 430 2.0 Array)   1435273_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142723
Ensembl peptide - ENSMUSP00000004343
Ensembl peptide - ENSMUSP00000142361
Ensembl peptide - ENSMUSP00000142470
NCBI entrez gene - 70560     See in Manteia.
MGI - MGI:1917810
RefSeq - XM_017319717
RefSeq - NM_027462
RefSeq - XM_006502052
RefSeq - XM_006502053
RefSeq - XM_011240223
RefSeq Peptide - NP_081738
swissprot - Q9CYK1
swissprot - A0A0G2JDR5
swissprot - A0A0G2JDG7
swissprot - Q8BZQ9
Ensembl - ENSMUSG00000004233
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wars2ENSDARG00000011801Danio rerio
 WARS2ENSGALG00000014772Gallus gallus
 WARS2ENSG00000116874Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001412  Aminoacyl-tRNA synthetase, class I, conserved site
 IPR002305  Aminoacyl-tRNA synthetase, class Ic
 IPR002306  Tryptophan-tRNA ligase
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR024109  Tryptophan-tRNA ligase, bacterial-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001570 vasculogenesis IDA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006436 tryptophanyl-tRNA aminoacylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005759 mitochondrial matrix ISO
 cellular_componentGO:0005886 plasma membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004830 tryptophan-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005330 cardiomyopathy "diseases of the heart (myocardium); may result from many causes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:80681]
Show

Allelic Composition: Slc26a5mpc234H/Slc26a5mpc234H
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

 MP:0006325 impaired hearing "reduced ability to percieve auditory stimuli" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Slc26a5mpc234H/Slc26a5mpc234H
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Trip13tm1.1(KOMP)Vlcg/Trip13tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Trip13tm1.1(KOMP)Vlcg/Ucd

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Trip13tm1.1(KOMP)Vlcg/Trip13tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Trip13tm1.1(KOMP)Vlcg/Ucd

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Trip13tm1.1(KOMP)Vlcg/Trip13tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Trip13tm1.1(KOMP)Vlcg/Ucd

 MP:0014143 decreased body fat mass "decreased physical bulk or volume of fat in the whole body" [MGI:csmith]
Show

Allelic Composition: Slc26a5mpc234H/Slc26a5mpc234H
Genetic Background: involves: BALB/c * C3H/HeH * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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