ENSMUSG00000004707


Mus musculus

Features
Gene ID: ENSMUSG00000004707
  
Biological name :Ly9
  
Synonyms : Ly9 / Q01965 / T-lymphocyte surface antigen Ly-9
  
Possible biological names infered from orthology : lymphocyte antigen 9 / Q9HBG7
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H3
Gene start: 171588624
Gene end: 171607410
  
Corresponding Affymetrix probe sets: 10360158 (MoGene1.0st)   1449156_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000137924
Ensembl peptide - ENSMUSP00000004827
Ensembl peptide - ENSMUSP00000069319
Ensembl peptide - ENSMUSP00000106908
NCBI entrez gene - 17085     See in Manteia.
MGI - MGI:96885
RefSeq - NM_001277968
RefSeq - NM_008534
RefSeq Peptide - NP_001264897
RefSeq Peptide - NP_032560
swissprot - Q01965
swissprot - E9PV93
swissprot - E9PX73
swissprot - M0QWN5
Ensembl - ENSMUSG00000004707
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LY9ENSG00000122224Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cd84 / CD84 antigen / Q9UIB8* / CD84 molecule*ENSMUSG0000003814715
Slamf7 / SLAM family member 7 / Q9NQ25*ENSMUSG0000003817913
Slamf9 / SLAM family member 9 / Q96A28*ENSMUSG0000002654813
Q9ET39 / Slamf6 / SLAM family member 6 / Q96DU3*ENSMUSG0000001531413


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0032740 positive regulation of interleukin-17 production IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0072540 T-helper 17 cell lineage commitment IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002434 abnormal T helper 2 morphology/development "anomalous structure, formation, or numbers of the subset of T helper cells that enhance humoral immunity and inhibit cell-mediated immune responses. These cells produce IL-4 and induce B cells to produce IgE and IgG1, while also supporting eosinophil and mast cell functions" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0003009 abnormal cytokine secretion "impairment or increase of the cellular release of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells " [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, smb:Susan M. Bello , Mouse Genome Informatics Curator]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0005095 decreased T cell proliferation "reduced clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr