ENSMUSG00000005267


Mus musculus

Features
Gene ID: ENSMUSG00000005267
  
Biological name :Zfp287
  
Synonyms : Q9EQB9 / Zfp287 / zinc finger protein 287
  
Possible biological names infered from orthology : Q9HBT7 / ZNF287
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B2
Gene start: 62700356
Gene end: 62731905
  
Corresponding Affymetrix probe sets: 10386921 (MoGene1.0st)   1425816_at (Mouse Genome 430 2.0 Array)   1436220_at (Mouse Genome 430 2.0 Array)   1439842_at (Mouse Genome 430 2.0 Array)   1444352_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114531
Ensembl peptide - ENSMUSP00000121717
Ensembl peptide - ENSMUSP00000141046
Ensembl peptide - ENSMUSP00000005399
Ensembl peptide - ENSMUSP00000117179
NCBI entrez gene - 170740     See in Manteia.
MGI - MGI:2176561
RefSeq - XM_017314304
RefSeq - NM_133208
RefSeq - XM_006532380
RefSeq - XM_006532382
RefSeq Peptide - NP_573471
swissprot - Q5SVS9
swissprot - Q9EQB9
swissprot - B7ZC81
swissprot - Q3UZW0
Ensembl - ENSMUSG00000005267
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CT027801.1ENSDARG00000096005Danio rerio
 Q9HBT7ENSG00000141040Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zfp712 / Q5SXM1* / ZNF678* / zinc finger protein 678*ENSMUSG0000009064136
Q7TSH9 / Zfp184 / zinc finger protein 184 (Kruppel-like) / Q99676* / ZNF184* / zinc finger protein 184*ENSMUSG0000000672036
Q8BI99 / Zfp879 / zinc finger protein 879 / B4DU55* / ZNF879*ENSMUSG0000004429634
Zfp612 / zinc finger protein 612 / ZNF23* / P17027* / zinc finger protein 23*ENSMUSG0000004467634
Zfp189 / zinc finger protein 189 / O75820* / ZNF189*ENSMUSG0000003963433
Zfp35 / P15620 / zinc finger protein 35ENSMUSG0000006328133
Gm14399ENSMUSG0000009009333
Zfp420 / zinc finger protein 420 / Q86YE8* / O75290* / ZNF573* / ZNF780A* / zinc finger protein 573* / zinc finger protein 780A*ENSMUSG0000005840232
Zfp2 / P08043 / zinc finger protein 2 / Q6ZN57* / ZFP2 zinc finger protein*ENSMUSG0000004932129
Zfp3 / Q8BLB0 / zinc finger protein 3 / Q96NJ6* / ZFP3 zinc finger protein*ENSMUSG0000004360228
Zkscan7 / zinc finger with KRAB and SCAN domains 7 / Q9P0L1*ENSMUSG0000006348828
Zfp11 / P10751 / zinc finger protein 11 / Q5SXM1* / ZNF678* / zinc finger protein 678*ENSMUSG0000005103424


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR003309  SCAN domain
 IPR008916  Retrovirus capsid, C-terminal
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0042035 regulation of cytokine biosynthetic process IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000480 increased number of ribs "greater than normal numbers of the pairs of bony structures that make up the body wall" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0003047 abnormal thoracic vertebrae morphology "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0003048 abnormal cervical vertebrae morphology "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Nsd3tm1b(EUCOMM)Hmgu/Nsd3tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nsd3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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