ENSMUSG00000006310


Mus musculus

Features
Gene ID: ENSMUSG00000006310
  
Biological name :Zbtb32
  
Synonyms : Q9JKD9 / Zbtb32 / zinc finger and BTB domain containing 32
  
Possible biological names infered from orthology : Q9Y2Y4
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B1
Gene start: 30589681
Gene end: 30598909
  
Corresponding Affymetrix probe sets: 10562044 (MoGene1.0st)   1432459_a_at (Mouse Genome 430 2.0 Array)   1447330_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000103785
Ensembl peptide - ENSMUSP00000103786
NCBI entrez gene - 58206     See in Manteia.
MGI - MGI:1891838
RefSeq - XM_011250663
RefSeq - NM_021397
RefSeq - XM_006540245
RefSeq - XM_006540246
RefSeq - XM_006540248
RefSeq Peptide - NP_067372
swissprot - Q9JKD9
swissprot - B2RQ06
Ensembl - ENSMUSG00000006310
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9Y2Y4ENSG00000011590Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zbtb16 / zinc finger and BTB domain containing 16 / Q05516*ENSMUSG0000006668728
Zbtb39 / zinc finger and BTB domain containing 39 / O15060*ENSMUSG0000004461721


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001817 regulation of cytokine production IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0042098 T cell proliferation IMP
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0000228 nuclear chromosome IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002123 abnormal hematopoiesis "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Il23atm1Dnax/Il23atm1Dnax
Genetic Background: involves: 129 * C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Fgf5tm1Tzi/Fgf5tm1Tzi,Fgf6tm1Thbr/Fgf6tm1Thbr,Fgf7tm1Efu/Fgf7tm1Efu
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129S4/SvJae * 129X1/SvJ

 MP:0003009 abnormal cytokine secretion "impairment or increase of the cellular release of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells " [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, smb:Susan M. Bello , Mouse Genome Informatics Curator]
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Allelic Composition: Erbb2tm7(Erbb2)Mul/Erbb2tm1Haus
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c

Allelic Composition: Zbtb32tm2Ppp/Zbtb32tm2Ppp
Genetic Background: involves: 129S1/Sv

 MP:0005348 increased T cell proliferation "increased clonal expansion of naive T cells in response to stimuli" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Erbb2tm7(Erbb2)Mul/Erbb2tm1Haus
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c

Allelic Composition: Zbtb32tm1Iho/Zbtb32tm1Iho
Genetic Background: involves: C57BL/6

Allelic Composition: Zbtb32tm2Ppp/Zbtb32tm2Ppp
Genetic Background: involves: 129S1/Sv

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
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Allelic Composition: Ins2Akita/Ins2Akita,Itga1tm1Gdnr/Itga1tm1Gdnr
Genetic Background: C.Cg-Ins2Akita Itga1tm1Gdnr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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