ENSMUSG00000006589


Mus musculus

Features
Gene ID: ENSMUSG00000006589
  
Biological name :Aprt
  
Synonyms : Adenine phosphoribosyltransferase / Aprt / P08030
  
Possible biological names infered from orthology : P07741
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: E1
Gene start: 122574635
Gene end: 122576909
  
Corresponding Affymetrix probe sets: 10582390 (MoGene1.0st)   1423801_a_at (Mouse Genome 430 2.0 Array)   1451703_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148607
Ensembl peptide - ENSMUSP00000148745
Ensembl peptide - ENSMUSP00000148652
Ensembl peptide - ENSMUSP00000006764
Ensembl peptide - ENSMUSP00000148477
NCBI entrez gene - 11821     See in Manteia.
MGI - MGI:88061
RefSeq - NM_009698
RefSeq Peptide - NP_033828
swissprot - A0A1D5RM31
swissprot - A0A1D5RLR6
swissprot - P08030
Ensembl - ENSMUSG00000006589
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 aprtENSDARG00000003519Danio rerio
 APRTENSGALG00000031000Gallus gallus
 APRTENSG00000198931Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000836  Phosphoribosyltransferase domain
 IPR005764  Adenine phosphoribosyl transferase
 IPR029057  Phosphoribosyltransferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006166 purine ribonucleoside salvage IMP
 biological_processGO:0006168 adenine salvage IMP
 biological_processGO:0007595 lactation IEA
 biological_processGO:0007625 grooming behavior IGI
 biological_processGO:0009116 nucleoside metabolic process IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0044209 AMP salvage IEA
 biological_processGO:0046083 adenine metabolic process IMP
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0002055 adenine binding IDA
 molecular_functionGO:0003999 adenine phosphoribosyltransferase activity IMP
 molecular_functionGO:0016208 AMP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Purine salvage


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000208 decreased hematocrit "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
Show

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0000538 abnormal urinary bladder morphology "malformation of the inflatable musculomembranous bag for holding urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0001259 abnormal body weight "anomaly in average weight compared to the norm" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Aprttm1Jat/Aprttm1Jat,Spp1tm1Rit/Spp1tm1Rit
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Aprttm1Jat/Aprttm1Jat,Spp1tm1Rit/Spp1tm1Rit
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0001263 weight loss "progressive reduction of body weight below normal average for age" [J:45400]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001429 dehydration "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053]
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Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001505 hunched posture "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001510 abnormal coat appearance "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0001511 disheveled coat "coat that looks generally unkempt" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0001762 polyuria "increased volume of urine produced and excreted" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0001859 kidney inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001921 reduced fertility "diminished ability to produce live offspring" [J:65030]
Show

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Aprttm1Jat/Aprttm1Jat,Spp1tm1Rit/Spp1tm1Rit
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Aprttm1Jat/Aprttm1Jat,Spp1tm1Rit/Spp1tm1Rit
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0002705 dilated renal tubules "enlarged lumens of the loops of Henle and/or collecting ducts of the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0002708 kidney stones "calculi occurring in the kidney" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Aprttm1Jat/Aprt+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0002989 small kidney "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0003014 abnormal kidney medulla morphology "anomalous structure of the inner portion of the kidney consisting of the renal pyramids" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:88636, smb:Susan M. Bello , Mouse Genome Informatics Curator]
Show

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0003215 renal interstitial fibrosis "formation of fibrous tissue within the interstices of the kidney as a result of repair or a reactive process" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0003311 aminoaciduria "excretion of amino acids in the urine, especially in excessive amounts" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:66560]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0003606 kidney failure "cessation of renal function" [ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003670 dilated glomerular capsule "an expansion in volume of the expanded beginning of a nephron that contains the glomerulus" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:91499]
Show

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0003918 decreased kidney weight "reduced heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission]
Show

Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003985 renal fibrosis "formation of fibrous tissue in the kidney as a result of repair or a reactive process" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004154 renal tubular necrosis "pathological cell death in the proximal and/or distal renal tubules, usually due to irreversible damage " [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004756 abnormal proximal convoluted tubule morphology "any structural anomaly of the convoluted portion of the duct system of the nephron that extends from the renal glomeurlar capsule in the kidney cortex into the kidney medulla where it joins the loop of Henle; fluid entering the proximal convoluted tubule is reabsorbed into the peritubular capillaries, including approximately two-thirds of the filtered salt and water and all filtered organic solutes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0004970 kidney atrophy "wasting of the kidney due to injury or disease, resulting in reduced size" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005558 decreased creatinine clearance "less than the normal amount of this creatine metabolite filtered by the kidneys in a specific period of time; indicative of kidney function" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0009643 abnormal urine homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

 MP:0009645 crystalluria "excretion of crystalline material in the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Vri/Aprttm1Vri
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0011346 renal tubule atrophy "acquired diminution of the size of the loops of Henle, the proximal convoluted tubule or the distal convoluted tubule associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:anna]
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Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0011402 renal cast "any of the various casts formed from gelled protein precipitated in the distal convoluted tubules and collecting ducts of nephrons and molded to the tubular or duct lumen which dislodge and pass into the urine; types named for their constituent material include acellular casts (e.g. granular, hyaline, waxy, or fatty casts) and cellular casts (e.g. red or white blood cell casts)" [MGI:anna]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0011403 pyelonephritis "a diffuse pyogenic infection of the pelvis and parenchyma of the kidney; an ascending urinary tract infection that has reached the pyelum or pelvis of the kidney usually resulting from noncontagious bacterial infection of the bladder" [MGI:anna]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0011413 colorless urine "absence of the usual straw-coloration of the urine" [MGI:anna]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0011422 kidney medulla atrophy "acquired diminution of the size of the inner portion of the kidney consisting of the renal pyramids, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:anna]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0011423 kidney cortex atrophy "acquired diminution of the size of the outer portion of the kidney located between the renal capsule and the renal medulla, associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:anna]
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Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: 129P2/OlaHsd-Aprttm1Dwm

 MP:0011424 decreased urine uric acid level "abnormally low amount in the urine of the final oxidation product of purine catabolism in humans and primates, but which in rodents and most other mammals is normally is further oxidized by uricase to allantoin that is excreted in the urine" [MGI:anna]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0011477 abnormal urine nucleoside level "any change in the urinary level of glycosylamines consisting of a nucleobase bound to a ribose or deoxyribose sugar via a beta-glycosidic linkage, including cytidine, uridine, adenosine, guanosine, thymidine and inosine and deoxynucleosides" [MGI:csmith]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Aprttm1Dwm/Aprttm1Dwm
Genetic Background: involves: 129P2/OlaHsd * BALB/c

Allelic Composition: Aprttm1Jat/Aprttm1Jat,Spp1tm1Rit/Spp1tm1Rit
Genetic Background: involves: 129S2/SvPas * 129S7/SvEvBrd

 MP:0011625 cystolithiasis "caliculi, or a solid concretion or crystal aggregation, found in the urinary bladder; often embedded in a glycoprotein matrix which may also contain some nonglycoproteins when associated with infection" [MGI:csmith]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0011844 kidney collecting duct atrophy "acquired diminution of the size of the kidney collecting ducts associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes" [MGI:anna]
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Allelic Composition: Aprttm1Jat/Aprttm1Jat
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0011941 increased fluid intake "increase in the total amount of fluid taken in over time when compared to the normal state" [MGI:csmith]
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Allelic Composition: C3ar1tm1Raw/C3ar1+
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000006589 Aprt / P08030 / Adenine phosphoribosyltransferase / P07741*  / complex






 

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