ENSMUSG00000006948


Mus musculus

Features
Gene ID: ENSMUSG00000006948
  
Biological name :Klk4
  
Synonyms : Kallikrein-4 / Klk4 / Q9Z0M1
  
Possible biological names infered from orthology : kallikrein related peptidase 4 / Q9Y5K2
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 43881160
Gene end: 43885804
  
Corresponding Affymetrix probe sets: 10552532 (MoGene1.0st)   1420763_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000007161
NCBI entrez gene - 56640     See in Manteia.
MGI - MGI:1861379
RefSeq - NM_019928
RefSeq Peptide - NP_064312
swissprot - A0A1R3UDT0
swissprot - Q9Z0M1
Ensembl - ENSMUSG00000006948
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000034771Gallus gallus
 KLK4ENSG00000167749Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klk5 / kallikrein related-peptidase 5 / Q9Y337*ENSMUSG0000007415540
Klk12 / kallikrein related peptidase 12 / Q9UKR0*ENSMUSG0000004443038
Klk7 / Q91VE3 / Kallikrein-7 / P49862* / kallikrein related peptidase 7*ENSMUSG0000003071335
Klk10 / kallikrein related peptidase 10 / O43240*ENSMUSG0000003069330


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0022617 extracellular matrix disassembly IMP
 biological_processGO:0030163 protein catabolic process IMP
 biological_processGO:0031214 biomineral tissue development IEA
 biological_processGO:0097186 amelogenesis ISO
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Dlx5tm1(cre/ERT2)Zjh/Dlx5+
Genetic Background: involves: C57BL/6 * SJL

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dlx5tm1(cre/ERT2)Zjh/Dlx5+
Genetic Background: involves: C57BL/6 * SJL

 MP:0002576 abnormal enamel morphology "malformation of the hard outer coating of the exposed portion of the tooth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:71126, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dlx5tm1(cre/ERT2)Zjh/Dlx5+
Genetic Background: involves: C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr