ENSMUSG00000044430


Mus musculus

Features
Gene ID: ENSMUSG00000044430
  
Biological name :Klk12
  
Synonyms : kallikrein related peptidase 12 / Klk12
  
Possible biological names infered from orthology : Q9UKR0
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B3
Gene start: 43768897
Gene end: 43773585
  
Corresponding Affymetrix probe sets: 10552475 (MoGene1.0st)   1453495_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000014063
Ensembl peptide - ENSMUSP00000103604
NCBI entrez gene - 69511     See in Manteia.
MGI - MGI:1916761
RefSeq - XM_017312288
RefSeq - NM_027097
RefSeq - XM_006541174
RefSeq - XM_017312287
RefSeq Peptide - NP_081373
swissprot - B2RVZ0
Ensembl - ENSMUSG00000044430
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000034771Gallus gallus
 KLK12ENSG00000186474Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Klk5 / kallikrein related-peptidase 5 / Q9Y337*ENSMUSG0000007415544
Klk7 / Q91VE3 / Kallikrein-7 / P49862* / kallikrein related peptidase 7*ENSMUSG0000003071343
Klk10 / kallikrein related peptidase 10 / O43240*ENSMUSG0000003069342
Klk4 / Q9Z0M1 / Kallikrein-4 / Q9Y5K2* / kallikrein related peptidase 4*ENSMUSG0000000694839


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis ISO
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity ISO
 molecular_functionGO:0008236 serine-type peptidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000055095 Q8BT20 / Spink6 / serine peptidase inhibitor, Kazal type 6 / Q6UWN8*  / complex / reaction






 

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