ENSMUSG00000007892


Mus musculus

Features
Gene ID: ENSMUSG00000007892
  
Biological name :Rplp1
  
Synonyms : P47955 / ribosomal protein, large, P1 / Rplp1
  
Possible biological names infered from orthology : P05386 / ribosomal protein lateral stalk subunit P1
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: B
Gene start: 61913284
Gene end: 61914542
  
Corresponding Affymetrix probe sets: 10581495 (MoGene1.0st)   10594248 (MoGene1.0st)   1416277_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000008036
NCBI entrez gene - 56040     See in Manteia.
MGI - MGI:1927099
RefSeq - NM_018853
RefSeq Peptide - NP_061341
swissprot - P47955
swissprot - Q58E35
Ensembl - ENSMUSG00000007892
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rplp1ENSDARG00000021864Danio rerio
 RPLP1ENSGALG00000030878Gallus gallus
 RPLP1ENSG00000137818Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm10073 / RPLP1* / P05386* / ribosomal protein lateral stalk subunit P1*ENSMUSG0000006001997


Protein motifs (from Interpro)
Interpro ID Name
 IPR027534  Ribosomal protein L12 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002181 cytoplasmic translation IBA
 biological_processGO:0006414 translational elongation IEA
 biological_processGO:0006417 regulation of translation IMP
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0045860 positive regulation of protein kinase activity IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit IBA
 molecular_functionGO:0003735 structural constituent of ribosome IBA
 molecular_functionGO:0030295 protein kinase activator activity IBA


Pathways (from Reactome)
Pathway description
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000477 abnormal intestine morphology "malformation of the digestive tube passing from the stomach to the anus" [J:48968]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0000585 kinked tail "a sharp bend or zig-zag in the tail" [J:61295]
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Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0000592 short tail "reduced length of tail compared to control " [J:55583]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0000598 abnormal liver morphology "malformation or absence of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:23170]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0000706 small thymus "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0001606 impaired hematopoiesis "atypical process of blood cell formation with the result of fewer of these cells being formed" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0002111 abnormal tail morphology "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0009703 decreased birth body size "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0011167 abnormal adipose tissue development "anomaly in the process of the formation of the connective tissue composed of fat cells enmeshed in areolar tissue" [MESH:A10.165.114, MGI:csmith]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0011179 decreased erythroblast number "reduced number of the nucleated precursor of erythrocytes" [MGI:csmith]
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Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0011239 abnormal skin coloration "a variation in an expected skin color or complexion that may be due to inflammation, pigment defects or other causes" [MGI:llw2]
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Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

 MP:0013176 abnormal tail position or orientation " tail is displaced from the normal location and/or does not orient in a typical pattern" [MGI:anna]
Show

Allelic Composition: Lifrtm1Imx/Lifr+
Genetic Background: B6;129S7-Lifrtm1Imx/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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