ENSMUSG00000009995


Mus musculus

Features
Gene ID: ENSMUSG00000009995
  
Biological name :Taz
  
Synonyms : tafazzin / Taz
  
Possible biological names infered from orthology : Q16635
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: A7.3
Gene start: 74281912
Gene end: 74290151
  
Corresponding Affymetrix probe sets: 10600357 (MoGene1.0st)   1416207_at (Mouse Genome 430 2.0 Array)   1453785_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135593
Ensembl peptide - ENSMUSP00000135013
Ensembl peptide - ENSMUSP00000135308
Ensembl peptide - ENSMUSP00000065270
Ensembl peptide - ENSMUSP00000109818
Ensembl peptide - ENSMUSP00000114496
Ensembl peptide - ENSMUSP00000115153
Ensembl peptide - ENSMUSP00000117206
Ensembl peptide - ENSMUSP00000121031
Ensembl peptide - ENSMUSP00000134745
NCBI entrez gene - 66826     See in Manteia.
MGI - MGI:109626
RefSeq - XM_011247664
RefSeq - NM_001173547
RefSeq - NM_001242615
RefSeq - NM_001242616
RefSeq - NM_001290738
RefSeq - NM_181516
RefSeq - XM_006528244
RefSeq - XM_006528246
RefSeq - XM_006528247
RefSeq - XM_006528248
RefSeq - XM_006528249
RefSeq - XM_006528250
RefSeq - XM_011247662
RefSeq Peptide - NP_001277667
RefSeq Peptide - NP_852657
RefSeq Peptide - NP_001229545
RefSeq Peptide - NP_001229544
RefSeq Peptide - NP_001167018
swissprot - I7HJS2
swissprot - J3JS92
swissprot - F6TQ32
swissprot - Q810E8
swissprot - Q91WF0
swissprot - B7FAU2
swissprot - F6V7B7
swissprot - H3BJJ8
swissprot - H3BK99
swissprot - H3BKZ8
Ensembl - ENSMUSG00000009995
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tazENSDARG00000041421Danio rerio
 TAZENSG00000102125Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000872  Tafazzin
 IPR002123  Phospholipid/glycerol acyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006644 phospholipid metabolic process IEA
 biological_processGO:0006936 muscle contraction ISO
 biological_processGO:0007007 inner mitochondrial membrane organization IBA
 biological_processGO:0007507 heart development ISO
 biological_processGO:0007519 skeletal muscle tissue development ISO
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016567 protein ubiquitination IMP
 biological_processGO:0030097 hemopoiesis ISO
 biological_processGO:0032049 cardiolipin biosynthetic process ISO
 biological_processGO:0032981 mitochondrial respiratory chain complex I assembly ISO
 biological_processGO:0035965 cardiolipin acyl-chain remodeling IBA
 biological_processGO:0042407 cristae formation ISO
 biological_processGO:0042775 mitochondrial ATP synthesis coupled electron transport ISO
 biological_processGO:0046471 phosphatidylglycerol metabolic process ISO
 biological_processGO:0048738 cardiac muscle tissue development ISO
 biological_processGO:0060048 cardiac muscle contraction ISO
 biological_processGO:1900210 positive regulation of cardiolipin metabolic process IEA
 biological_processGO:2001171 positive regulation of ATP biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031224 intrinsic component of membrane IBA
 cellular_componentGO:0031966 mitochondrial membrane IBA
 molecular_functionGO:0008374 O-acyltransferase activity IBA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0047184 1-acylglycerophosphocholine O-acyltransferase activity ISO


Pathways (from Reactome)
Pathway description
Acyl chain remodeling of CL


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptentm2Mak/Ptentm2Mak,Trp53tm1Brn/Trp53tm1Brn,Tg(Nes-cre/ERT2,-ALPP)1Sbk/0
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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