ENSMUSG00000010721


Mus musculus

Features
Gene ID: ENSMUSG00000010721
  
Biological name :Lmbr1
  
Synonyms : Limb region 1 protein / Lmbr1 / Q9JIT0
  
Possible biological names infered from orthology : limb development membrane protein 1 / Q8WVP7
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: B1
Gene start: 29229802
Gene end: 29378390
  
Corresponding Affymetrix probe sets: 10528877 (MoGene1.0st)   10528880 (MoGene1.0st)   1425605_a_at (Mouse Genome 430 2.0 Array)   1426272_at (Mouse Genome 430 2.0 Array)   1426273_at (Mouse Genome 430 2.0 Array)   1442371_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000143316
Ensembl peptide - ENSMUSP00000142755
Ensembl peptide - ENSMUSP00000143348
Ensembl peptide - ENSMUSP00000142987
Ensembl peptide - ENSMUSP00000058405
Ensembl peptide - ENSMUSP00000136160
NCBI entrez gene - 56873     See in Manteia.
MGI - MGI:1861746
RefSeq - XM_017321034
RefSeq - XM_006535765
RefSeq - XM_006535767
RefSeq - XM_006535768
RefSeq - XM_006535770
RefSeq - XM_011249782
RefSeq - XM_011249783
RefSeq - NM_020295
RefSeq - XM_006535764
RefSeq Peptide - NP_064691
swissprot - A0A0G2JFU9
swissprot - J3QM78
swissprot - A0A0G2JF18
swissprot - A0A0G2JFX9
swissprot - Q9JIT0
Ensembl - ENSMUSG00000010721
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lmbr1ENSDARG00000024092Danio rerio
 LMBR1ENSGALG00000030379Gallus gallus
 LMBR1ENSG00000105983Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lmbr1l / Q9D1E5 / Protein LMBR1L / Q6UX01* / limb development membrane protein 1 like*ENSMUSG0000002299959


Protein motifs (from Interpro)
Interpro ID Name
 IPR006876  LMBR1-like membrane protein
 IPR008075  Lipocalin-interacting membrane receptor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035116 embryonic hindlimb morphogenesis ISO
 biological_processGO:0042733 embryonic digit morphogenesis IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000552 abnormal radius morphology "malformation of the short bone of the lateral forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Lmbr1tm1Kng/Del(5D5Mit73-D5Mit351)5Jcs
Genetic Background: mixed

 MP:0000554 abnormal carpal bone morphology "malformation of the nine nodular bones of the joint between the forelimb bones and the front paws consisting of the scapholunar, triangular, greater multiangular, lesser multiangular, capitate, hamate, centrale and the sesamoids" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]
Show

Allelic Composition: Akt3tm1Hem/Akt3tm1Hem
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Lmbr1tm1Kng/Del(5D5Mit73-D5Mit351)5Jcs
Genetic Background: mixed

 MP:0000564 syndactyly "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Akt3tm1Hem/Akt3tm1Hem
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Lmbr1tm1Kng/Del(5D5Mit73-D5Mit351)5Jcs
Genetic Background: mixed

 MP:0000565 oligodactyly "congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Akt3tm1Hem/Akt3tm1Hem
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Lmbr1tm1Kng/Del(5D5Mit73-D5Mit351)5Jcs
Genetic Background: mixed

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Axin1Fu-Tg1/Axin1tm1(Axin2)Cos
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA/J * FVB/N

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Lats2tm1Dgen/Lats2tm1Dgen
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002543 brachyphalangia "abnormally short phalanges" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Akt3tm1Hem/Akt3tm1Hem
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Lmbr1tm1Kng/Del(5D5Mit73-D5Mit351)5Jcs
Genetic Background: mixed

 MP:0005108 abnormal ulna morphology "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
Show

Allelic Composition: Lmbr1tm1Kng/Del(5D5Mit73-D5Mit351)5Jcs
Genetic Background: mixed

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Lmbr1tm1Kng/Del(5D5Mit73-D5Mit351)5Jcs
Genetic Background: mixed

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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