ENSMUSG00000013160


Mus musculus

Features
Gene ID: ENSMUSG00000013160
  
Biological name :Atp6v0d1
  
Synonyms : Atp6v0d1 / P51863 / V-type proton ATPase subunit d 1
  
Possible biological names infered from orthology : ATPase H+ transporting V0 subunit d1 / P61421
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: D3
Gene start: 105524465
Gene end: 105566047
  
Corresponding Affymetrix probe sets: 10581289 (MoGene1.0st)   10338524 (MoGene1.0st)   10339286 (MoGene1.0st)   10339341 (MoGene1.0st)   10339365 (MoGene1.0st)   10339388 (MoGene1.0st)   10340106 (MoGene1.0st)   10340925 (MoGene1.0st)   10341233 (MoGene1.0st)   10343182 (MoGene1.0st)   10342445 (MoGene1.0st)   1415671_at (Mouse Genome 430 2.0 Array)   1442216_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000013304
NCBI entrez gene - 11972     See in Manteia.
MGI - MGI:1201778
RefSeq - NM_013477
RefSeq Peptide - NP_038505
swissprot - P51863
Ensembl - ENSMUSG00000013160
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6PGV1ENSDARG00000069090Danio rerio
 ATP6V0D1ENSGALG00000002237Gallus gallus
 P61421ENSG00000159720Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80SY3 / Atp6v0d2 / V-type proton ATPase subunit d 2 / Q8N8Y2* / ATPase H+ transporting V0 subunit d2*ENSMUSG0000002823867


Protein motifs (from Interpro)
Interpro ID Name
 IPR002843  ATPase, V0 complex, c/d subunit
 IPR016727  ATPase, V0 complex, subunit d
 IPR035067  V-type ATPase subunit c
 IPR036079  V-type ATP synthase subunit C-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006879 cellular iron ion homeostasis IEA
 biological_processGO:0007034 vacuolar transport IBA
 biological_processGO:0007035 vacuolar acidification IBA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0015991 ATP hydrolysis coupled proton transport IEA
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0036295 cellular response to increased oxygen levels IEA
 biological_processGO:0060271 cilium assembly ISS
 cellular_componentGO:0005765 lysosomal membrane IBA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0016471 vacuolar proton-transporting V-type ATPase complex IEA
 cellular_componentGO:0033179 proton-transporting V-type ATPase, V0 domain IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043679 axon terminus IEA
 molecular_functionGO:0008553 proton-exporting ATPase activity, phosphorylative mechanism IDA
 molecular_functionGO:0015078 proton transmembrane transporter activity IEA
 molecular_functionGO:0046961 proton-transporting ATPase activity, rotational mechanism IBA


Pathways (from Reactome)
Pathway description
ROS, RNS production in phagocytes
Insulin receptor recycling
Transferrin endocytosis and recycling
Ion channel transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002059 abnormal seminal gland morphology "anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0002591 decreased mean corpuscular volume "less than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0005642 decreased mean corpuscular hemoglobin concentration "less than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936]
Show

Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
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Allelic Composition: Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+
Genetic Background: C57BL/6N-Atp1a3tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028238 Q80SY3 / Atp6v0d2 / V-type proton ATPase subunit d 2 / Q8N8Y2* / ATPase H+ transporting V0 subunit d2*  / complex






 

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