ENSMUSG00000013593


Mus musculus

Features
Gene ID: ENSMUSG00000013593
  
Biological name :Ndufs2
  
Synonyms : NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial / Ndufs2 / Q91WD5
  
Possible biological names infered from orthology : NADH:ubiquinone oxidoreductase core subunit S2 / O75306
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: H3
Gene start: 171234853
Gene end: 171251388
  
Corresponding Affymetrix probe sets: 10360076 (MoGene1.0st)   1451096_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000013737
Ensembl peptide - ENSMUSP00000141942
Ensembl peptide - ENSMUSP00000141370
Ensembl peptide - ENSMUSP00000106950
NCBI entrez gene - 226646     See in Manteia.
MGI - MGI:2385112
RefSeq - NM_153064
RefSeq Peptide - NP_694704
swissprot - A0A0A6YXD3
swissprot - A0A0A6YW30
swissprot - D3YXT0
swissprot - Q91WD5
Ensembl - ENSMUSG00000013593
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ndufs2ENSDARG00000007526Danio rerio
 NDUFS2ENSGALG00000041418Gallus gallus
 NDUFS2ENSG00000158864Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001135  NADH-quinone oxidoreductase, subunit D
 IPR014029  NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site
 IPR022885  NAD(P)H-quinone oxidoreductase subunit D/H
 IPR029014  [NiFe]-hydrogenase, large subunit


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0042775 mitochondrial ATP synthesis coupled electron transport IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005747 mitochondrial respiratory chain complex I IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070469 respiratory chain IEA
 molecular_functionGO:0003954 NADH dehydrogenase activity ISO
 molecular_functionGO:0008137 NADH dehydrogenase (ubiquinone) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016651 oxidoreductase activity, acting on NAD(P)H IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048038 quinone binding IEA
 molecular_functionGO:0051287 NAD binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Respiratory electron transport
Complex I biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024082 Q9CWG8 / Ndufaf7 / Protein arginine methyltransferase NDUFAF7, mitochondrial / Q7L592* / NADH:ubiquinone oxidoreductase complex assembly factor 7*  / complex






 

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