ENSMUSG00000013822


Mus musculus

Features
Gene ID: ENSMUSG00000013822
  
Biological name :Elof1
  
Synonyms : Elof1 / Mus musculus ELF1 homolog, elongation factor 1 (Elof1), transcript variant 4, mRNA. / P60003
  
Possible biological names infered from orthology : elongation factor 1 homolog / P60002
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: A3
Gene start: 22112989
Gene end: 22117172
  
Corresponding Affymetrix probe sets: 10591735 (MoGene1.0st)   1423820_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000150536
Ensembl peptide - ENSMUSP00000128173
Ensembl peptide - ENSMUSP00000149885
Ensembl peptide - ENSMUSP00000013966
Ensembl peptide - ENSMUSP00000150169
NCBI entrez gene - 66126     See in Manteia.
MGI - MGI:1913376
RefSeq - XM_017313508
RefSeq - NM_001357311
RefSeq - NM_001357314
RefSeq - NM_170777
RefSeq - XM_017313506
RefSeq - XM_017313507
RefSeq Peptide - NP_001344241
RefSeq Peptide - NP_001344242
RefSeq Peptide - NP_001344243
RefSeq Peptide - NP_740747
RefSeq Peptide - NP_001344239
RefSeq Peptide - NP_001344240
RefSeq Peptide - NP_001344238
swissprot - P60003
swissprot - Q545S6
Ensembl - ENSMUSG00000013822
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 elof1ENSDARG00000099453Danio rerio
 ELOF1ENSG00000130165Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007808  Transcription elongation factor 1
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IBA
 biological_processGO:0006414 translational elongation IEA
 biological_processGO:0048096 chromatin-mediated maintenance of transcription IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0008023 transcription elongation factor complex IBA
 molecular_functionGO:0000993 RNA polymerase II core binding IBA
 molecular_functionGO:0003746 translation elongation factor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H

 MP:0005633 increased circulating sodium level "greater than the normal concentration in the blood of this metallic element, the most plentiful extracellular ion in the body and the principal determinant of extracellular fluid volume" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Elmod1tm1b(EUCOMM)Hmgu/Elmod1tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Elmod1tm1b(EUCOMM)Hmgu/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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