ENSMUSG00000014355


Mus musculus

Features
Gene ID: ENSMUSG00000014355
  
Biological name :Anapc1
  
Synonyms : Anapc1 / Anaphase-promoting complex subunit 1 / P53995
  
Possible biological names infered from orthology : Q9H1A4
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: F1
Gene start: 128610104
Gene end: 128687391
  
Corresponding Affymetrix probe sets: 10487513 (MoGene1.0st)   10338354 (MoGene1.0st)   10338446 (MoGene1.0st)   10338830 (MoGene1.0st)   10338870 (MoGene1.0st)   10338973 (MoGene1.0st)   10339023 (MoGene1.0st)   10339156 (MoGene1.0st)   10339225 (MoGene1.0st)   10339354 (MoGene1.0st)   10339746 (MoGene1.0st)   10339754 (MoGene1.0st)   10339849 (MoGene1.0st)   10339940 (MoGene1.0st)   10340055 (MoGene1.0st)   10340212 (MoGene1.0st)   10340271 (MoGene1.0st)   10340379 (MoGene1.0st)   10340490 (MoGene1.0st)   10340545 (MoGene1.0st)   10340752 (MoGene1.0st)   10340852 (MoGene1.0st)   10341083 (MoGene1.0st)   10341112 (MoGene1.0st)   10341240 (MoGene1.0st)   10341526 (MoGene1.0st)   10341645 (MoGene1.0st)   10341944 (MoGene1.0st)   10342098 (MoGene1.0st)   10342157 (MoGene1.0st)   10342314 (MoGene1.0st)   10342366 (MoGene1.0st)   10342368 (MoGene1.0st)   10342416 (MoGene1.0st)   10342460 (MoGene1.0st)   10342632 (MoGene1.0st)   10342811 (MoGene1.0st)   10342813 (MoGene1.0st)   10342952 (MoGene1.0st)   10343152 (MoGene1.0st)   10343227 (MoGene1.0st)   10343294 (MoGene1.0st)   10343351 (MoGene1.0st)   10343509 (MoGene1.0st)   10343640 (MoGene1.0st)   10343721 (MoGene1.0st)   10343746 (MoGene1.0st)   10343760 (MoGene1.0st)   10343933 (MoGene1.0st)   10344111 (MoGene1.0st)   10344126 (MoGene1.0st)   10344402 (MoGene1.0st)   10344493 (MoGene1.0st)   10338156 (MoGene1.0st)   10338376 (MoGene1.0st)   10338419 (MoGene1.0st)   10338512 (MoGene1.0st)   10338713 (MoGene1.0st)   10338829 (MoGene1.0st)   10339091 (MoGene1.0st)   10339163 (MoGene1.0st)   10339238 (MoGene1.0st)   10339278 (MoGene1.0st)   10339464 (MoGene1.0st)   10339465 (MoGene1.0st)   10339768 (MoGene1.0st)   10340010 (MoGene1.0st)   10340089 (MoGene1.0st)   10340196 (MoGene1.0st)   10340288 (MoGene1.0st)   10340469 (MoGene1.0st)   10341209 (MoGene1.0st)   10341445 (MoGene1.0st)   10341463 (MoGene1.0st)   10341613 (MoGene1.0st)   10341654 (MoGene1.0st)   10341751 (MoGene1.0st)   10342040 (MoGene1.0st)   10342423 (MoGene1.0st)   10342540 (MoGene1.0st)   10342566 (MoGene1.0st)   10342624 (MoGene1.0st)   10342861 (MoGene1.0st)   10342880 (MoGene1.0st)   10342936 (MoGene1.0st)   10343148 (MoGene1.0st)   10343204 (MoGene1.0st)   10343341 (MoGene1.0st)   10343343 (MoGene1.0st)   10343757 (MoGene1.0st)   10343952 (MoGene1.0st)   10344252 (MoGene1.0st)   10344310 (MoGene1.0st)   10344347 (MoGene1.0st)   10344577 (MoGene1.0st)   1415680_at (Mouse Genome 430 2.0 Array)   1417570_at (Mouse Genome 430 2.0 Array)   1434443_at (Mouse Genome 430 2.0 Array)   1434444_s_at (Mouse Genome 430 2.0 Array)   1444271_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000105962
Ensembl peptide - ENSMUSP00000014499
Ensembl peptide - ENSMUSP00000105961
NCBI entrez gene - 17222     See in Manteia.
MGI - MGI:103097
RefSeq - NM_008569
RefSeq - XM_011239332
RefSeq Peptide - NP_032595
swissprot - A2ATQ5
swissprot - P53995
swissprot - Q6PG65
Ensembl - ENSMUSG00000014355
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 anapc1ENSDARG00000075687Danio rerio
 ENSGALG00000008254Gallus gallus
 ANAPC1ENSG00000153107Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002015  Proteasome/cyclosome repeat
 IPR024990  Anaphase-promoting complex subunit 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070979 protein K11-linked ubiquitination IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005680 anaphase-promoting complex IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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