ENSMUSG00000018862


Mus musculus

Features
Gene ID: ENSMUSG00000018862
  
Biological name :Otop3
  
Synonyms : Mus musculus otopetrin 3 (Otop3), transcript variant 2, mRNA. / Otop3 / Q80UF9
  
Possible biological names infered from orthology : otopetrin 3 / Q7RTS5
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 115334731
Gene end: 115346927
  
Corresponding Affymetrix probe sets: 10382492 (MoGene1.0st)   1429036_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019006
Ensembl peptide - ENSMUSP00000102153
NCBI entrez gene - 69602     See in Manteia.
MGI - MGI:1916852
RefSeq - XM_006534116
RefSeq - NM_001347647
RefSeq - NM_027132
RefSeq Peptide - NP_001334576
RefSeq Peptide - NP_081408
swissprot - Q80UF9
swissprot - F8VQ32
Ensembl - ENSMUSG00000018862
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OTOP3ENSGALG00000028214Gallus gallus
 OTOP3ENSG00000182938Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Otop2 / Q80SX5 / Otopetrin-2 / Q7RTS6*ENSMUSG0000005020139
Otop1 / otopetrin-1 / Q7RTM1*ENSMUSG0000005159628


Protein motifs (from Interpro)
Interpro ID Name
 IPR004878  Otopetrin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho/Disc1del
Genetic Background: 129S2/SvPasCrl-Disc1del Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho

 MP:0006035 abnormal mitochondrial morphology "anomalous structure of the mitochondria" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho/Disc1del
Genetic Background: 129S2/SvPasCrl-Disc1del Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho

 MP:0006149 blurred vision "loss of visiual acuity or ability to distinguish small details" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho/Disc1del
Genetic Background: 129S2/SvPasCrl-Disc1del Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho

 MP:0008067 retinal ganglion cell degeneration "degeneration or loss of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho/Disc1del
Genetic Background: 129S2/SvPasCrl-Disc1del Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho

 MP:0011635 abnormal mitochondrial crista morphology "Any of the inward folds of the mitochondrial inner membrane; crista number, extent, and shape differ in mitochondria from different tissues and organisms; crista appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found; the shape can vary with the respiratory state of the mitochondria" [GO:0030061]
Show

Allelic Composition: Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho/Disc1del
Genetic Background: 129S2/SvPasCrl-Disc1del Disc1tm1(DISC1/DISC1FP1,DISC1FP1/DISC1,DISC1)Xzho

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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