ENSMUSG00000051596


Mus musculus

Features
Gene ID: ENSMUSG00000051596
  
Biological name :Otop1
  
Synonyms : Otop1 / otopetrin-1
  
Possible biological names infered from orthology : Q7RTM1
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: B3
Gene start: 38275972
Gene end: 38304217
  
Corresponding Affymetrix probe sets: 10521574 (MoGene1.0st)   1438448_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000061805
Ensembl peptide - ENSMUSP00000109734
NCBI entrez gene - 21906     See in Manteia.
MGI - MGI:2388363
RefSeq - NM_172709
RefSeq Peptide - NP_766297
swissprot - E9QMU2
swissprot - A0A0R4J1J4
Ensembl - ENSMUSG00000051596
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OTOP1ENSDARG00000021566Danio rerio
 OTOP1ENSGALG00000030356Gallus gallus
 OTOP1ENSG00000163982Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Otop2 / Q80SX5 / Otopetrin-2 / Q7RTS6*ENSMUSG0000005020130
Otop3 / Q80UF9 / Mus musculus otopetrin 3 (Otop3), transcript variant 2, mRNA. / Q7RTS5* / otopetrin 3*ENSMUSG0000001886228


Protein motifs (from Interpro)
Interpro ID Name
 IPR004878  Otopetrin


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001405 impaired coordination "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Otop1ied/Otop1ied
Genetic Background: involves: C3HeB/FeJ * C57BL/6

 MP:0001504 abnormal posture "atypical position of the limbs or carriage of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18984]
Show

Allelic Composition: Smad2tm1Rob/Smad2tm1Rob
Genetic Background: involves: 129S/SvEv

Allelic Composition: Otop1ied/Otop1ied
Genetic Background: involves: C3HeB/FeJ * C57BL/6

 MP:0001522 impaired swimming "reduced ability or inability to swim" [J:45446, J:39081]
Show

Allelic Composition: Smad2tm1Rob/Smad2tm1Rob
Genetic Background: involves: 129S/SvEv

Allelic Composition: Otop1mlh/Otop1mlh
Genetic Background: involves: BALB/cJ

Allelic Composition: Otop1tlt/Otop1tlt
Genetic Background: B6.Cg-Otop1tlt/J

Allelic Composition: Otop1ied/Otop1ied
Genetic Background: involves: C3HeB/FeJ * C57BL/6

Allelic Composition: Otop1tm1Dor/Otop1tm1Dor
Genetic Background: Not Specified

Allelic Composition: Otop1mlh/Otop1mlh
Genetic Background: BALB/c-Otop1mlh

 MP:0001523 impaired righting response "reduced ability or greater amount of time needed to recover from supine position" [J:25565]
Show

Allelic Composition: Otop1ied/Otop1ied
Genetic Background: involves: C3HeB/FeJ * C57BL/6

 MP:0002066 abnormal motor capabilities/coordination/movement "altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Fah2R/Fah2R
Genetic Background: BALB/cRl

 MP:0002757 reduced vertical activity "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Otop1ied/Otop1ied
Genetic Background: involves: C3HeB/FeJ * C57BL/6

 MP:0002856 abnormal vestibular ganglion morphology "malformation of the group of neurons associated with the vestibular part of the eighth cranial nerve that are involved in equilibration" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Otop1tlt/Otop1tlt
Genetic Background: B6.Cg-Otop1tlt/J

 MP:0002978 absent otoliths "absence of the crystalline calciferous particles adhering to the otolithic membrane" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Otop1mlh/Otop1mlh
Genetic Background: involves: BALB/cJ

Allelic Composition: Otop1tlt/Otop1tlt
Genetic Background: B6.Cg-Otop1tlt/J

Allelic Composition: Otop1ied/Otop1ied
Genetic Background: involves: C3HeB/FeJ * C57BL/6

Allelic Composition: Otop1tm1Dor/Otop1tm1Dor
Genetic Background: Not Specified

 MP:0004742 abnormal vestibular system physiology "any functional anomaly of the sensory system responsible for the sense of head position and movement of the body through space; such anomalies may include impaired balance, dizziness, poor regulation of postural muscle tone and inability to detect quick movements of the head " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Otop1tm1Dor/Otop1tm1Dor
Genetic Background: Not Specified

 MP:0004813 absent linear vestibular evoked potential "absence of the biphasic response elicited by linear acceleration transients (usually jerk pulses to an animal s head)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Otop1tlt/Otop1tlt
Genetic Background: B6.Cg-Otop1tlt/J

 MP:0005191 head tilt "condition in which the portion of the body containing the brain and organs of sight, hearing, taste, and smell lists to the side" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Smad2tm1Rob/Smad2tm1Rob
Genetic Background: involves: 129S/SvEv

Allelic Composition: Otop1mlh/Otop1mlh
Genetic Background: involves: BALB/cJ

Allelic Composition: Otop1tlt/Otop1tlt
Genetic Background: B6.Cg-Otop1tlt/J

Allelic Composition: Otop1ied/Otop1ied
Genetic Background: involves: C3HeB/FeJ * C57BL/6

Allelic Composition: Otop1mlh/Otop1mlh
Genetic Background: BALB/c-Otop1mlh

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr